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一例与听力丧失相关的胰岛素依赖型或非胰岛素依赖型糖尿病家族病例。

A familial case of insulin dependent or non-insulin dependent diabetes mellitus associated with hearing loss.

作者信息

Hiramatsu K, Arimori S, Tsuji K

机构信息

Department of Internal Medicine, School of Medicine, Tokai, Isehara, Kanagawa, Japan.

出版信息

Jpn J Med. 1988 May;27(2):211-5. doi: 10.2169/internalmedicine1962.27.211.

Abstract

Aggregation of diabetes and hearing loss in a family is observed in some hereditary disease. All members of the present family are affected with sensory hearing loss and diabetes mellitus. Diabetes types observed were insulin dependent diabetes mellitus (IDDM) in the proposita and the sister, non-insulin dependent diabetes mellitus (NIDDM) in the brother, and impaired glucose tolerance in the mother. The combination of hearing loss and diabetes and the concordant expression of IDDM or NIDDM in the siblings have not hitherto been described in any hereditary syndrome. This family may exhibit a new hereditary syndrome which is characterized by diabetes and hearing loss.

摘要

在一些遗传性疾病中可观察到一个家族中糖尿病与听力损失的聚集现象。本家族的所有成员均患有感音神经性听力损失和糖尿病。观察到的糖尿病类型为:先证者及其妹妹为胰岛素依赖型糖尿病(IDDM),弟弟为非胰岛素依赖型糖尿病(NIDDM),母亲为糖耐量受损。听力损失与糖尿病的组合以及兄弟姐妹中IDDM或NIDDM的一致表现迄今尚未在任何遗传性综合征中被描述过。这个家族可能表现出一种以糖尿病和听力损失为特征的新的遗传性综合征。

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