The Department of Otolaryngology in the Zhongshan City People's Hospital, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, P.R. China.
Sci Prog. 2021 Apr-Jun;104(2):368504211028367. doi: 10.1177/00368504211028367.
This study aimed to review our experience with the clinical characteristics and management of deep neck infections (DNIs) and determine the changing trends of their characteristics over time in southern China. Patients diagnosed with a DNI between January 2009 and December 2018 were screened retrospectively for their demographic characteristics, etiology of infection, site of infection, microbiology, treatment, and complications. In total, 127 patients were included: 41 (32.3%) were treated between 2009 and 2013 (group A), and 86 (67.7%) were treated between 2014 and 2018 (group B). The most common site of infection in group A was the parapharyngeal space (15 patients, 36.6%), while that in group B involved multiple spaces (36 patients, 41.9%). The leucocyte count (×10 cells/L) was 13.23 ± 4.19 in group A and 16.04 ± 4.33 in group B ( < 0.001). was the most common bacteria in both groups. The mean hospital stay was 21.46 ± 33.09 days in group A and 10.44 ± 6.19 days in group B. The rate of diabetes mellitus (DM) in group A was lower than that in group B (8/41 and 33/86, respectively; = 0.034). Airway obstruction was the most common complication in both groups. DNIs are more likely to show multi-space involvement, affect more DM patients, and be associated with higher leucocyte counts over time. We infer that the duration from morbidity to admission and that from admission to operation play roles in the successful management of DNIs, possibly causing fewer complications, lower mortality rates, and shorter hospital stays. DM patients require increased attention.
本研究旨在回顾我们在诊治深部颈部感染(DNI)方面的经验,并确定中国南方 DNI 特征随时间变化的趋势。回顾性筛选了 2009 年 1 月至 2018 年 12 月期间诊断为 DNI 的患者,记录其人口统计学特征、感染病因、感染部位、微生物学、治疗和并发症。共纳入 127 例患者:41 例(32.3%)于 2009 年至 2013 年期间治疗(A 组),86 例(67.7%)于 2014 年至 2018 年期间治疗(B 组)。A 组最常见的感染部位是咽旁间隙(15 例,36.6%),B 组则涉及多个间隙(36 例,41.9%)。A 组的白细胞计数(×10 细胞/L)为 13.23±4.19,B 组为 16.04±4.33( < 0.001)。两组均以 为最常见的细菌。A 组的平均住院时间为 21.46±33.09 天,B 组为 10.44±6.19 天。A 组糖尿病(DM)患者比例低于 B 组(8/41 和 33/86, = 0.034)。两组均以气道梗阻为最常见的并发症。随着时间的推移,DNI 更可能表现为多间隙受累,影响更多的 DM 患者,并与更高的白细胞计数相关。我们推断,发病到入院时间以及入院到手术时间在 DNI 的成功治疗中起作用,可能导致更少的并发症、更低的死亡率和更短的住院时间。DM 患者需要更多关注。