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Determination of lopinavir/ritonavir concentrations in four different oral solutions for the application of antiretroviral therapy in very young, HIV-1-infected children.

作者信息

von Hentig Nils, Angioni Carlo, Königs Christoph

机构信息

Internal Medicine II, HIVCENTER, Goethe University Hospital, Frankfurt, Germany.

Institute of Clinical Pharmacology, Goethe University Hospital, Frankfurt, Germany.

出版信息

South Afr J HIV Med. 2021 May 11;22(1):1222. doi: 10.4102/sajhivmed.v22i1.1222. eCollection 2021.

DOI:10.4102/sajhivmed.v22i1.1222
PMID:34192069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8182455/
Abstract
摘要

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2
Long-term follow-up of 414 HIV-infected Romanian children and adolescents receiving lopinavir/ritonavir-containing highly active antiretroviral therapy.对414名接受含洛匹那韦/利托那韦的高效抗逆转录病毒治疗的罗马尼亚HIV感染儿童和青少年进行长期随访。
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本文引用的文献

1
Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood.洛匹那韦/利托那韦的群体药代动力学：从婴儿期到成年期不同制剂和人体发育过程中的变化。
J Clin Pharmacol. 2018 Dec;58(12):1604-1617. doi: 10.1002/jcph.1293. Epub 2018 Sep 25.
2
Neurocognitive development in HIV-positive children is correlated with plasma viral loads in early childhood.感染艾滋病毒儿童的神经认知发育与幼儿期的血浆病毒载量相关。
Medicine (Baltimore). 2017 Jun;96(23):e6867. doi: 10.1097/MD.0000000000006867.
3
Virological response and resistances over 12 months among HIV-infected children less than two years receiving first-line lopinavir/ritonavir-based antiretroviral therapy in Cote d'Ivoire and Burkina Faso: the MONOD ANRS 12206 cohort.在科特迪瓦和布基纳法索，接受基于洛匹那韦/利托那韦的一线抗逆转录病毒疗法的2岁以下感染艾滋病毒儿童12个月期间的病毒学反应和耐药性：MONOD ANRS 12206队列研究
J Int AIDS Soc. 2017 Apr 25;20(1):21362. doi: 10.7448/IAS.20.01.21362.
4
Impact of lopinavir-ritonavir exposure in HIV-1 infected children and adolescents in Madrid, Spain during 2000-2014.2000年至2014年期间，洛匹那韦-利托那韦暴露对西班牙马德里感染HIV-1的儿童和青少年的影响。
PLoS One. 2017 Mar 28;12(3):e0173168. doi: 10.1371/journal.pone.0173168. eCollection 2017.
5
Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.洛匹那韦/利托那韦与拉米夫定及阿巴卡韦或齐多夫定用于儿科固定剂量复方制剂的剂量比。
Antivir Ther. 2015;20(2):225-33. doi: 10.3851/IMP2876. Epub 2014 Oct 3.
6
Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: recommendations from the National Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.HIV暴露儿童和HIV感染儿童机会性感染的预防和治疗指南：美国国立卫生研究院、疾病控制与预防中心、美国传染病学会HIV医学协会、儿科传染病学会及美国儿科学会的建议
Pediatr Infect Dis J. 2013 Nov;32 Suppl 2(0 2):i-KK4. doi: 10.1097/01.inf.0000437856.09540.11.
7
Pharmacokinetics of pediatric lopinavir/ritonavir tablets in children when administered twice daily according to FDA weight bands.根据美国食品药品监督管理局（FDA）体重范围，儿童每日两次服用洛匹那韦/利托那韦片的药代动力学。
Pediatr Infect Dis J. 2014 Mar;33(3):301-5. doi: 10.1097/INF.0000000000000014.
8
The International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma: a global proficiency testing program.国际抗逆转录病毒药物血浆测量实验室间质量控制计划：一项全球性的能力验证计划。
Ther Drug Monit. 2011 Apr;33(2):239-43. doi: 10.1097/FTD.0b013e31820fa528.
9
Predictive factors for response to a boosted dual HIV-protease inhibitor therapy with saquinavir and lopinavir in extensively pre-treated patients.在接受过广泛治疗的患者中，使用沙奎那韦和洛匹那韦的强化双重HIV蛋白酶抑制剂疗法疗效的预测因素。
Antivir Ther. 2007;12(8):1237-46.
10
Population analysis of weight-, age-, and sex-related differences in the pharmacokinetics of lopinavir in children from birth to 18 years.对出生至18岁儿童洛匹那韦药代动力学中体重、年龄和性别相关差异的群体分析。
Antimicrob Agents Chemother. 2006 Nov;50(11):3548-55. doi: 10.1128/AAC.00943-05. Epub 2006 Aug 28.