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约旦年轻人群对婚前基因筛查的认知

The Perception of Premarital Genetic Screening within Young Jordanian Individuals.

作者信息

Altaany Zaid, Khabour Omar F, Alzoubi Karem H, Alkaraki Almuthanna K, Al-Taani Ghaith

机构信息

Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.

Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Public Health Genomics. 2021;24(3-4):182-188. doi: 10.1159/000517162. Epub 2021 Jun 30.

Abstract

BACKGROUND

During the past two decades, the attention of public health has been drawn to premarital genetic screening (PGS) programs to reduce birth defects and avoid genetic disorders. In Jordan, the high rate of genetic hemoglobinopathies compelled the government to implement an obligatory PGS program before marriage. Therefore, the objective of this study was to investigate the knowledge, opinion, and practice of young Jordanians concerning PGS.

METHODS

Using a pretested questionnaire, this cross-sectional study was conducted on a convenience sample from Jordan. The measures included respondents' demographics, and beliefs/opinions regarding PGS.

RESULTS

A total of 432 participants completed the survey. The majority (87.8%) had a positive attitude toward PGS program. Reasons behind this positive attitude were preventing transmission of genetic diseases, reducing family breakdown/psychosocial problems, and financial burdens of having a child with genetic disease. In fact, 49.8% of participants were willing to change their marriage decision in case of receiving incompatible results. Moreover, most of the participants (75.1%) demanded the implementation of a law that prohibits incompatible marriages. A positive attitude toward PGS was found to be associated with female gender and having a university education.

CONCLUSIONS

Young Jordanians have a positive attitude toward the implementation of PGS. Yet, educational programs should be drawn up to the target population before getting married emphasizing the important role of PGS in the wellness of the community.

摘要

背景

在过去二十年中,婚前基因筛查(PGS)项目已引起公共卫生领域的关注,以减少出生缺陷并避免遗传疾病。在约旦,遗传性血红蛋白病的高发病率促使政府实施婚前强制基因筛查项目。因此,本研究的目的是调查约旦年轻人对婚前基因筛查的知识、看法和实践情况。

方法

本横断面研究采用预先测试的问卷,对来自约旦的便利样本进行调查。测量内容包括受访者的人口统计学信息以及对婚前基因筛查的信念/看法。

结果

共有432名参与者完成了调查。大多数人(87.8%)对婚前基因筛查项目持积极态度。这种积极态度背后的原因包括防止遗传疾病的传播、减少家庭破裂/心理社会问题以及生育患有遗传疾病孩子的经济负担。事实上,49.8%的参与者表示如果收到不相容的结果,愿意改变他们的婚姻决定。此外,大多数参与者(75.1%)要求实施一项禁止不相容婚姻的法律。研究发现,对婚前基因筛查持积极态度与女性性别和接受过大学教育有关。

结论

约旦年轻人对实施婚前基因筛查持积极态度。然而,在结婚前应为目标人群制定教育计划,强调婚前基因筛查在社区健康中的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf4/9984666/0cbdadc68b57/nihms-1877778-f0001.jpg

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