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免疫功能正常患者播散性近平滑念珠菌感染伴嗜酸性粒细胞增多:一例报告。

Disseminated Trichosporon asahii infection presenting as eosinophilia in an immunocompetent patient: A case report.

机构信息

Department of Laboratory Medicine, Qingdao University Medical College Affiliated Yantai Yuhuangding Hospital, Yantai, China.

Department of Laboratory Medicine,Yantai Affiliated Hospital of Binzhou Medical College, Yantai, China.

出版信息

Indian J Med Microbiol. 2021 Oct-Dec;39(4):552-555. doi: 10.1016/j.ijmmb.2021.05.021. Epub 2021 Jun 27.

DOI:10.1016/j.ijmmb.2021.05.021
PMID:34193352
Abstract

Trichosporon are naturally found in external environments and are a part of the normal flora of the human skin, respiratory tract, and gastrointestinal tract. Disseminated Trichosporon infection occurs sporadically in patients with immunodeficiency, and is mainly manifested as blood, urine, catheter, and thorax/peritoneum infections, rarely as lymphatic, liver and spleen infections. Elevated blood eosinophil granulocyte from Trichosporon infection have rarely been reported. Here, we report a rare Case of eosinophilia associated with lymphatic and liver and spleen infections due to Trichosporon asahii in an immunocompetent patient. No reports of eosinophilia from Trichosporon infections other than lung, to our knowledge, have been published.

摘要

新生隐球菌天然存在于外部环境中,是人体皮肤、呼吸道和胃肠道正常菌群的一部分。播散性新生隐球菌感染在免疫功能低下的患者中偶有发生,主要表现为血液、尿液、导管和胸/腹腔感染,很少有淋巴、肝脏和脾脏感染。新生隐球菌感染导致的血液嗜酸性粒细胞增多症鲜有报道。在此,我们报道了一例罕见的免疫功能正常患者感染近平滑念珠菌导致的淋巴、肝脏和脾脏感染伴嗜酸性粒细胞增多症的病例。据我们所知,除肺部外,尚无其他新生隐球菌感染导致嗜酸性粒细胞增多症的报道。

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