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散发性子宫淋巴管平滑肌瘤病(LAM):一例起源于子宫下段的罕见病例报告及简要综述

Sporadic uterine Lymphangioleiomyomatosis (LAM): Report of a unique case arising in the lower uterine segment with short review.

作者信息

Pongsuvareeyakul Tip, Maleki Sara, DeNardo Bradley D, Dizon Don S, Phornphutkul Chanika, Singh Kamaljeet

机构信息

Department of Pathology and Laboratory Medicine, Women & Infants Hospital of Rhode Island, Brown University, Providence, RI, United States.

Department of Pathology and Laboratory Medicine, Warren Alpert Medical School of Brown University, Providence, RI, United States.

出版信息

Gynecol Oncol Rep. 2021 Jun 17;37:100812. doi: 10.1016/j.gore.2021.100812. eCollection 2021 Aug.

DOI:10.1016/j.gore.2021.100812
PMID:34195331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8239460/
Abstract

•Extrapulmonary lymphangioleiomyomatosis is rare and can be associated with tuberous sclerosis.•Recognition of lymphangioleiomyomatosis is important for early disease screening and genetic testing.•Lymphangioleiomyomatosis in lower uterine segment is very rare and can be overlooked.

摘要

•肺外淋巴管平滑肌瘤病罕见,可与结节性硬化症相关。

•认识淋巴管平滑肌瘤病对早期疾病筛查和基因检测很重要。

•子宫下段淋巴管平滑肌瘤病非常罕见,可能被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c2/8239460/17b6396e0e03/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c2/8239460/441095b28c5b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c2/8239460/17b6396e0e03/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c2/8239460/441095b28c5b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c2/8239460/17b6396e0e03/gr2.jpg

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本文引用的文献

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Perivascular epithelioid cell tumors (PEComa) of the gynecologic tract.妇科生殖道血管周上皮样细胞瘤(PEComa)。
Genes Chromosomes Cancer. 2021 Mar;60(3):168-179. doi: 10.1002/gcc.22908. Epub 2020 Nov 6.
2
Extrapulmonary uterine lymphangioleiomyomatosis (LAM) and dysfunctional uterine bleeding: the first presentation of LAM in a tuberous sclerosis complex patient.肺外子宫淋巴管平滑肌瘤病(LAM)与功能失调性子宫出血:1例结节性硬化症患者首次表现为LAM
BMJ Case Rep. 2019 Feb 25;12(2):e226358. doi: 10.1136/bcr-2018-226358.
3
Lymphangioleiomyoma of the Uterus and Pelvic Lymph Nodes: A Report of 3 Cases, Including the Potentially Earliest Manifestation of Extrapulmonary Lymphangioleiomyomatosis.
子宫和盆腔淋巴结淋巴管平滑肌瘤病:3 例报告,包括肺外淋巴管平滑肌瘤病的潜在最早表现。
Int J Gynecol Pathol. 2020 May;39(3):227-232. doi: 10.1097/PGP.0000000000000589.
4
Pelvic lymphangioleiomyomatosis treated successfully with everolimus: Two case reports with literature review.依维莫司成功治疗盆腔淋巴管平滑肌瘤病:两例病例报告并文献复习
Medicine (Baltimore). 2017 Mar;96(10):e4562. doi: 10.1097/MD.0000000000004562.
5
A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus.一例淋巴管平滑肌瘤病合并子宫内膜癌及重度系统性红斑狼疮。
BMC Cancer. 2016 Jul 4;16:390. doi: 10.1186/s12885-016-2413-z.
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Malignant presentation of uterine lymphangioleiomyomatosis.子宫淋巴管平滑肌瘤病的恶性表现
Taiwan J Obstet Gynecol. 2015 Oct;54(5):603-7. doi: 10.1016/j.tjog.2015.08.015.
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Use of sirolimus in the treatment of lymphangioleiomyomatosis: favorable responses in patients with different extrapulmonary manifestations.西罗莫司在淋巴管平滑肌瘤病治疗中的应用:不同肺外表现患者的良好反应。
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