Work & Mental Health Research Unit, Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.
School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.
Depress Anxiety. 2021 Sep;38(9):917-924. doi: 10.1002/da.23192. Epub 2021 Jul 1.
To evaluate the impact of providing personalized depression risk information on self-help and help-seeking behaviors among individuals who are at high risk of having a major depressive episode (MDE).
In a mixed methods randomized controlled trial, participants who were at high risk of having a MDE, were recruited from across Canada, and were randomized into intervention (n = 358) and control (n = 354) groups. Participants in the intervention group received their personalized depression risk estimated by sex-specific risk prediction models for MDE. All participants were assessed at baseline, 6 and 12 months.
Repeated measure mixed effects modeling showed significant between group differences in self-help scores. In the complete case analysis, the between group difference in mean self-help change score was 1.13 at 12 months (effect size = 0.16). Among participants who reported "fair" or "poor health," the between group difference in mean self-help change score was 2.78 at 12 months (effect size = 0.35). The qualitative data revealed three themes and the findings are consistent with the quantitative results.
Providing personalized depression risk information has a positive impact on self-help in high-risk individuals, particularly in those with poor health.
评估为有发生重度抑郁发作(MDE)高风险的个体提供个性化抑郁风险信息对自助和寻求帮助行为的影响。
在一项混合方法随机对照试验中,从加拿大各地招募了有 MDE 高风险的参与者,并将其随机分为干预组(n=358)和对照组(n=354)。干预组的参与者收到了他们的个性化抑郁风险估计值,这些估计值是通过特定于性别的 MDE 风险预测模型得出的。所有参与者在基线、6 个月和 12 个月时进行评估。
重复测量混合效应模型显示,自助得分存在显著的组间差异。在完整案例分析中,12 个月时的平均自助变化评分的组间差异为 1.13(效应大小=0.16)。在报告“一般”或“较差”健康状况的参与者中,12 个月时的平均自助变化评分的组间差异为 2.78(效应大小=0.35)。定性数据揭示了三个主题,发现结果与定量结果一致。
提供个性化抑郁风险信息对高风险个体的自助行为有积极影响,特别是对健康状况较差的个体。