Sellers Zachary M, Barakat Monique T, Abu-El-Haija Maisam
Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Stanford University, Palo Alto, CA 94304, USA.
Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA 94304, USA.
J Clin Med. 2021 Jun 8;10(12):2545. doi: 10.3390/jcm10122545.
Acute pancreatitis (AP) is associated with significant morbidity and mortality, and it substantially contributes to the healthcare burden of gastrointestinal disease and quality of life in children and adults. AP across the lifespan is characterized by similarities and differences in epidemiology, diagnostic modality, etiologies, management, adverse events, long-term outcomes, and areas in greatest need of research. In this review, we touch on each of these shared and distinctive features of AP in children and adults, with an emphasis on recent advances in the conceptualization and management of AP.
急性胰腺炎(AP)与显著的发病率和死亡率相关,并且在很大程度上加重了儿童和成人胃肠道疾病的医疗负担以及对生活质量的影响。在整个生命周期中,AP在流行病学、诊断方式、病因、管理、不良事件、长期预后以及最需要研究的领域等方面既有相似之处,也存在差异。在本综述中,我们探讨了儿童和成人AP的这些共同和独特特征,重点关注AP概念化和管理方面的最新进展。