Torres-Muñoz Javier, Jimenez-Fernandez Carlos Alberto, Murillo-Alvarado Jennifer, Torres-Figueroa Sofia, Castro Juan Pablo
Department of Pediatrics, Health Faculty, School of Medicine, Universidad del Valle, Cali 100-00, Colombia.
Health Sciences Faculty, School of Medicine, Universidad ICESI, Cali 122-135, Colombia.
Nutrients. 2021 Jun 25;13(7):2187. doi: 10.3390/nu13072187.
Breast milk is widely recognized as the best source of nutrition for both full term and premature babies. We aimed to identify clinical results of the implementation of a breast milk bank for premature infants under 37 weeks in a level III hospital. 722 neonates under 37 weeks, hospitalized in the Neonatal intensive care unit (ICU), who received human breast milk from the institution's milk bank 57% ( = 412) vs. mixed or artificial 32% ( = 229), at day 7 of life. An exploratory data analysis was carried out. Measures of central tendency and dispersion were used, strength of association of odds ratio (OR) and its confidence intervals (95% confidence interval (CI)). 88.5% had already received human milk before day 7 of life. Those who received human milk, due to their clinical condition, had 4 times a greater chance of being intubated (OR 4.05; 95% CI 1.80-9.11). Starting before day 7 of life decreases the opportunity to develop necrotizing enterocolitis by 82% (adjusted odds ratio (ORa) 0.18; 95% CI 0.03-0.97), intraventricular hemorrhage by 85% (ORa 0.15; 95% CI 0.06-0.45) and sepsis by 77% (ORa 0.23; 95% CI 0.15-0.33). Receiving human milk reduces the probability of complications related to prematurity, evidencing the importance that breast milk banks play in clinical practice.
母乳被广泛认为是足月儿和早产儿最佳的营养来源。我们旨在确定在一家三级医院为37周以下早产儿建立母乳库的临床效果。722名37周以下的新生儿入住新生儿重症监护病房(ICU),在出生第7天时,57%(n = 412)的婴儿接受了该机构母乳库提供的母乳,32%(n = 229)的婴儿接受了混合奶或人工喂养。进行了探索性数据分析。使用了集中趋势和离散度的测量方法、优势比(OR)及其置信区间(95%置信区间(CI))的关联强度。88.5%的婴儿在出生第7天之前就已经接受了母乳。由于临床状况,接受母乳的婴儿插管的几率高出4倍(OR 4.05;95% CI 1.80 - 9.11)。在出生第7天之前开始接受母乳可使坏死性小肠结肠炎的发病几率降低82%(调整优势比(ORa)0.18;95% CI 0.03 - 0.97),脑室内出血的发病几率降低85%(ORa 0.15;95% CI 0.06 - 0.45),败血症的发病几率降低77%(ORa 0.23;95% CI 0.15 - 0.33)。接受母乳可降低与早产相关的并发症的概率,这证明了母乳库在临床实践中的重要性。