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[肺部游离细胞成分对γ射线照射的反应]

[The reaction of free cellular elements of the lungs to gamma exposure].

作者信息

Kulikovskikh G I, Poplyko M G, Malenchenko A F

出版信息

Radiobiologiia. 1988 Jul-Aug;28(4):474-8.

PMID:3420218
Abstract

A quantitative composition of free cell elements and morphology and mitotic activity of macrophages were studied after gamma irradiation with doses of 25.8, 77.4, and 180.6 mC/kg. Morphological changes in the lungs and a deviation from the control values of an overall content of cell elements in washings were found to be a function of radiation dose. The discrepancy between the results obtained by other authors are attributed to a limited elimination of macrophages due to pulmonary edema and restoration of the number of macrophages due to a relatively moderate mitotic activity of these cells.

摘要

研究了在25.8、77.4和180.6 mC/kg剂量的γ射线照射后,游离细胞成分的定量组成以及巨噬细胞的形态和有丝分裂活性。发现肺部的形态变化以及冲洗液中细胞成分总含量与对照值的偏差是辐射剂量的函数。其他作者所得结果之间的差异归因于肺水肿导致巨噬细胞清除受限,以及这些细胞相对适度的有丝分裂活性导致巨噬细胞数量恢复。

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