糖尿病相关足部溃疡患者的认知障碍
Cognitive Impairment in People with Diabetes-Related Foot Ulceration.
作者信息
Siru Ranita, Burkhardt Melanie S, Davis Wendy A, Hiew Jonathan, Manning Laurens, Ritter Jens Carsten, Norman Paul E, Makepeace Ashley, Fegan Peter Gerry, Bruce David G, Davis Timothy M E, Hamilton Emma J
机构信息
Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Murdoch 6150, Australia.
Department of Clinical Psychology and Clinical Neuropsychology, Fiona Stanley and Fremantle Hospitals Group, Murdoch 6150, Australia.
出版信息
J Clin Med. 2021 Jun 25;10(13):2808. doi: 10.3390/jcm10132808.
AIMS
To determine whether there is an excess of cognitive impairment in patients with type 2 diabetes and foot ulceration.
METHODS
55 patients with type 2 diabetes and foot ulcers attending Multidisciplinary Diabetes Foot Ulcer clinics (MDFU cohort) were compared with 56 patients with type 2 diabetes attending Complex Diabetes clinics (CDC cohort) using commonly used screening tests for cognitive impairment (Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MOCA)), as well as foot self-care, mood and health literacy. MMSE was also compared between the MDFU cohort and a historical community-based cohort of patients with type 2 diabetes (FDS2 cohort).
RESULTS
Median MMSE scores were the same in all three groups (28/30). Median MOCA scores did not differ between the MDFU and CDC cohorts (25/30). There were no significant differences in the percentages of patients with MMSE ≤ 24 or MOCA ≤ 25 between MDFU and CDC cohorts (3.6% versus 10.7%, = 0.27 and 56.4% versus 51.8%, = 0.71, respectively), findings that did not change after adjustment for age, sex, education, diabetes duration, and random blood glucose.
CONCLUSIONS
Using conventionally applied instruments, patients with type 2 diabetes and foot ulceration have similar cognition compared with patients without, from either hospital-based clinic or community settings.
目的
确定2型糖尿病合并足部溃疡患者是否存在认知障碍过多的情况。
方法
使用常用的认知障碍筛查测试（简易精神状态检查表（MMSE）和蒙特利尔认知评估量表（MOCA）），以及足部自我护理、情绪和健康素养，将55名在多学科糖尿病足溃疡诊所就诊的2型糖尿病合并足部溃疡患者（MDFU队列）与56名在复杂糖尿病诊所就诊的2型糖尿病患者（CDC队列）进行比较。还将MDFU队列与一个基于社区的2型糖尿病患者历史队列（FDS2队列）的MMSE得分进行了比较。
结果
三组的MMSE中位数得分相同（28/30）。MDFU队列和CDC队列之间的MOCA中位数得分没有差异（25/30）。MDFU队列和CDC队列中MMSE≤24或MOCA≤25的患者百分比没有显著差异（分别为3.6%对10.7%，P = 0.27；56.4%对51.8%，P = 0.71），在对年龄、性别、教育程度、糖尿病病程和随机血糖进行调整后，这些结果没有改变。
结论
使用传统应用的工具，2型糖尿病合并足部溃疡患者与来自医院诊所或社区环境的无足部溃疡的患者相比，认知能力相似。
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