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化脓性脊椎骨髓炎患者随访影像学检查的意义

Interest of Follow-Up Radiological Imaging in Patients with Pyogenic Vertebral Osteomyelitis.

作者信息

Hecquet Sophie, Verhoeven Frank, Aubry Sébastien, Prati Clément, Wendling Daniel, Chirouze Catherine, Bouiller Kévin

机构信息

Department of Rheumatology, Besançon University Hospital, 25020 Besançon, France.

PEPITE EA4267, FHU INCREASE, Bourgogne Franche-Comté University, UFR Santé, 25020 Besançon, France.

出版信息

J Clin Med. 2021 Jun 18;10(12):2690. doi: 10.3390/jcm10122690.

Abstract

No recommendations are established for monitoring pyogenic vertebral osteomyelitis (PVO). Thus, the realization of systematic follow-up radiological imaging is controversial. The objective of this study was to evaluate the interest in follow-up radiological imaging in patients with PVO. We conducted a retrospective cohort analysis of patients with PVO who had both baseline and follow-up radiological imaging. We classified the follow-up images into two groups, improvement/stability, and deterioration, compared with the baseline data. For each patient, we compared their radiological imaging follow-up to their clinical-biological condition assessed at the same time. Eighty-six patients were included. The mean age was 68 years (±13). A total of 99 radiological imaging examinations at diagnosis and at follow-up were analyzed, 69 Magnetic Resonance Imaging (MRI), and 30 Computerized Tomography (CT scans). The mean delay between the follow-up radiological imaging and clinical evaluation was 2.8 +/- 2.1 months. Of the 36 patients with clinical and biological recovery, 24 patients (67%) had improved radiological imaging and 12 patients (34%) had radiological worsening (new abscesses ( = 4), extension of soft tissue infiltration ( = 2) and/or epiduritis ( = 2) or appearance of new locations ( = 1)). Among the 50 patients considered as unhealed, on the contrary, radiological imaging showed an improvement in imaging in 39 patients (78%) and a worsening in 11 patients (22%). Our study showed that there was no correlation between the clinical condition of patients and their follow-up radiological imaging in the context of PVO.

摘要

目前尚无针对化脓性脊椎骨髓炎(PVO)监测的相关建议。因此,进行系统性的随访放射影像学检查存在争议。本研究的目的是评估PVO患者进行随访放射影像学检查的价值。我们对有基线和随访放射影像学检查的PVO患者进行了回顾性队列分析。我们将随访图像与基线数据进行比较,分为改善/稳定和恶化两组。对于每位患者,我们将其放射影像学随访结果与其同时评估的临床生物学状况进行比较。共纳入86例患者。平均年龄为68岁(±13岁)。共分析了99次诊断时和随访时的放射影像学检查,其中69次为磁共振成像(MRI),30次为计算机断层扫描(CT扫描)。随访放射影像学检查与临床评估之间的平均间隔时间为2.8±2.1个月。在36例临床和生物学恢复的患者中,24例(67%)放射影像学检查有所改善,12例(34%)放射影像学检查恶化(新发脓肿(=4)、软组织浸润范围扩大(=2)和/或硬脊膜外炎(=2)或出现新发病灶(=1))。相反,在50例被认为未治愈的患者中,放射影像学检查显示39例(78%)有所改善,11例(22%)恶化。我们的研究表明,在PVO的情况下,患者的临床状况与其随访放射影像学检查之间没有相关性。

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