Sun Liqi, Huang Haojie, Jin Zhendong
Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Endosc Ultrasound. 2021 Jul-Aug;10(4):230-240. doi: 10.4103/EUS-D-20-00216.
Pancreatic cystic neoplasms (PCNs) are being detected increasingly frequently due to the widespread use of high-resolution abdominal imaging modalities. Some subtypes of PCNs have the potential for malignant transformation. Therefore, accurate diagnosis of PCNs is crucial to determine whether surgical resection or surveillance is the best management strategy. However, the current cross-section imaging modalities are not accurate enough to enable definite diagnoses. In the last decade, EUS-based techniques have emerged, aiming to overcome the limitations of standard cross-section imaging modalities. These novel EUS-based techniques were primarily designed to acquire distinct images to make radiological diagnoses, collect cyst fluid to undergo biochemical or molecular analyses, and obtain tissue to conclude the pathological diagnoses. In this article, we present a comprehensive and critical review of these emerging EUS techniques for the diagnosis of PCNs, with emphasis being placed on the advantages, feasibilities, diagnostic performances, and limitations of these novel techniques.
由于高分辨率腹部成像技术的广泛应用，胰腺囊性肿瘤（PCNs）的检出率日益增加。PCNs的某些亚型具有恶性转化的潜能。因此，准确诊断PCNs对于确定手术切除或监测是否为最佳管理策略至关重要。然而，目前的横断面成像技术尚不够精确，无法做出明确诊断。在过去十年中，基于超声内镜（EUS）的技术应运而生，旨在克服标准横断面成像技术的局限性。这些基于EUS的新技术主要用于获取清晰图像以进行放射学诊断、收集囊液进行生化或分子分析以及获取组织以得出病理诊断。在本文中，我们对这些新兴的用于诊断PCNs的EUS技术进行了全面而批判性的综述，重点阐述了这些新技术的优势、可行性、诊断性能及局限性。
