[模拟日光光动力疗法成功治疗皮肤利什曼病]
[Successful treatment of cutaneous leishmaniasis with simulated daylight photodynamic therapy].
作者信息
Hobelsberger Sarah, Krauß Marie-Paloma, Bogdan Christian, Aschoff Roland
机构信息
Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.
Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen-Nürnberg, Deutschland.
出版信息
Hautarzt. 2022 May;73(5):376-378. doi: 10.1007/s00105-021-04852-y. Epub 2021 Jul 2.
A 5-year-old Syrian boy , presented with a complex cutaneous leishmaniasis (CL) of the right ankle caused by Leishmania (L.) tropica. The patient received photodynamic therapy (PDT; 6 cycles with application of 5‑aminolevulinic acid and foil occlusion for 3 h). Due to pain during exposure to red light, exposure was continued with simulated daylight (sDL-PDT). The lesion healed with an atrophic scar. Due to fewer side effects and less pain, sDL-PDT seems to be a good therapeutic strategy for CL caused by L. tropica.
一名5岁的叙利亚男孩，患有由热带利什曼原虫引起的右踝部复杂性皮肤利什曼病（CL）。该患者接受了光动力疗法（PDT；应用5-氨基酮戊酸并使用箔片封闭3小时，共6个周期）。由于在红光照射期间疼痛，改用模拟日光继续照射（sDL-PDT）。病变愈合后留下萎缩性瘢痕。由于副作用较少且疼痛较轻，sDL-PDT似乎是治疗热带利什曼原虫引起的CL的良好治疗策略。
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