Department of Orthopaedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Department of Family Medicine, Ajou University Medical Center, Suwon, South Korea.
Int Orthop. 2021 Oct;45(10):2465-2471. doi: 10.1007/s00264-021-05129-8. Epub 2021 Jul 2.
The purpose of this study was to evaluate the complications and safety of transplanted organs after upper extremity surgery in patients taking immunosuppressants after solid organ transplantation (SOT).
Seventy-two transplant recipients underwent 99 upper extremity surgeries while on immunosuppressants after SOT at our institution between January 2009 and December 2018. We retrospectively reviewed the clinical data of these patients, including their demographic information and data related to the SOT and upper extremity surgery.
Trigger/tendon release (n = 31, 31.3%) was the most frequently performed upper extremity surgery, followed by incision and drainage for an infection (n = 16, 16.2%). Post-operative complications occurred after ten upper extremity operative procedures (10.1%), among which uncontrolled infection after surgery for an infection (n = 4) was the most common. According to the Clavien-Dindo classification, the complications of three surgical procedures were grade I, three were grade II, and four were grade III, and all were treatable. The occurrence rate of the complications was not significantly different between emergent and elective surgery. All transplanted organ-specific indicators did not worsen significantly after emergent or elective upper extremity surgery.
Since the function of the transplanted organ was well-preserved after emergent or elective upper extremity surgery, common upper extremity procedures do not seem to be a worrisome practice for SOT patients. However, when treating hand and upper extremity infections in SOT patients, surgeons should explain the possible need for multiple operations and the high complication rate.
本研究旨在评估接受实体器官移植(SOT)后免疫抑制治疗的患者行上肢手术后移植器官的并发症和安全性。
2009 年 1 月至 2018 年 12 月,我院对 72 例 SOT 后接受免疫抑制治疗的移植受者进行了 99 例上肢手术。我们回顾性分析了这些患者的临床资料,包括人口统计学信息、SOT 和上肢手术相关数据。
触发/肌腱松解术(n=31,31.3%)是最常进行的上肢手术,其次是感染切开引流术(n=16,16.2%)。10 例上肢手术(10.1%)后出现术后并发症,其中术后感染控制不佳(n=4)最为常见。根据 Clavien-Dindo 分级,3 例手术的并发症为Ⅰ级,3 例为Ⅱ级,4 例为Ⅲ级,均为可治疗性并发症。急诊手术和择期手术的并发症发生率无显著差异。所有移植器官特异性指标在急诊或择期上肢手术后均无明显恶化。
由于紧急或择期上肢手术后移植器官的功能得到很好的保留,因此常见的上肢手术似乎不会对 SOT 患者造成担忧。然而,当治疗 SOT 患者手部和上肢感染时,外科医生应向患者解释可能需要多次手术和高并发症发生率。