Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan; Department of Molecular Hematology, Karolinska Institute, Stockholm, Sweden.
Cell Stem Cell. 2021 Jul 1;28(7):1185-1187. doi: 10.1016/j.stem.2021.06.002.
In this issue of Cell Stem Cell, Grossmann et al. (2021) reconstructed the developmental history of the prostate gland in a 59-year-old male by 3D tracking of somatic mutations across 319 micro-dissected specimens. It provides a genetic picture of how the human prostate gland is shaped during embryogenesis, puberty, and adult life.
本期《细胞—干细胞》杂志上，Grossmann 等人（2021）通过对 319 个微切割样本中的体细胞突变进行 3D 追踪，重建了一位 59 岁男性前列腺的发育史。该研究提供了一幅人类前列腺在胚胎期、青春期和成年期发育过程中如何形成的遗传图谱。
