Department of Rehabilitation, Uonuma Kikan Hospital, 4132 Urasa, Minami Uonuma, Niigata 949-7302, Japan.
Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, 760 magarite, kikuchi-gun kikuyou-cho, Kumamoto 869-1106, Japan.
J Stroke Cerebrovasc Dis. 2021 Sep;30(9):105941. doi: 10.1016/j.jstrokecerebrovasdis.2021.105941. Epub 2021 Jun 30.
Phase angle, an assessment of muscle quality, might be a possible predictor of physical function in patients with an acute stroke; however, the evidence for the same is limited. Therefore, this study aimed to investigate whether phase angle is associated with improved physical function at discharge.
In this observational cohort study, we determined the phase angle in patients with an acute stroke using a portable, noninvasive multifrequency bio-impedance device. The primary objective was the assessment of physical function using the Functional Independence Measure motor (FIM-motor) at discharge in the acute phase. The secondary outcome was home discharge. Multiple regression analysis was used to determine the association between phase angle, FIM-motor score, and home discharge.
The study included 129 patients (78 men; mean age 75.2 years). Multiple linear regression analysis showed that the phase angle was independently associated with FIM-motor score at discharge in all models (Model 1: β= 0.27, p < 0.001; Model 2: β = 0.234, p < 0.001; Model 3: β = 0.201, p = 0.017). However, multiple logistic regression analysis showed that the phase angle was not associated with home discharge (p = 0.464).
The phase angle at the onset of a stroke, is an independent predictor of physical function at discharge in the acute phase. Our findings highlight the importance of determining the phase angle in patients with an acute stroke.
相位角是肌肉质量的评估指标，可能是预测急性脑卒中患者身体功能的一个潜在指标；然而，目前相关证据有限。因此，本研究旨在探讨相位角是否与急性脑卒中患者出院时的身体功能改善有关。
在这项观察性队列研究中，我们使用便携式、非侵入性多频生物阻抗设备来确定急性脑卒中患者的相位角。主要目的是在急性期使用功能性独立测量运动（FIM-motor）评估出院时的身体功能。次要结果是家庭出院。采用多元回归分析确定相位角、FIM-motor 评分和家庭出院之间的关联。
本研究共纳入 129 例患者（78 名男性；平均年龄 75.2 岁）。多元线性回归分析显示，在所有模型中，相位角与出院时的 FIM-motor 评分独立相关（模型 1：β=0.27，p<0.001；模型 2：β=0.234，p<0.001；模型 3：β=0.201，p=0.017）。然而，多元逻辑回归分析显示，相位角与家庭出院无关（p=0.464）。
脑卒中发病时的相位角是急性阶段出院时身体功能的独立预测指标。我们的研究结果强调了在急性脑卒中患者中确定相位角的重要性。
