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[秘鲁利马一家医院结核病患者中与重度勃起功能障碍(ED)相关的因素]

[Factors associated with high-grade Erectile Dysfunction (ED) in tuberculosis patients from a hospital in Lima, Peru].

作者信息

Reyes-Paredes Marjorie, Valladares-Garrido Mario Josué, Ichiro Peralta Christopher, Dominguez-Troncos Helena, Grandez-Urbina Antonio

机构信息

Facultad de Medicina. Universidad Ricardo Palma. Lima. Perú.

Universidad Continental. Lima. Perú.

出版信息

Arch Esp Urol. 2021 Jul;74(6):579-586.

Abstract

OBJECTIVE

To determine the prevalence and factors associated with high-grade ED in Lima, Peru.

MATERIAL AND METHODS

Analytical cross-sectional study in tuberculosis patients treated in an out patient clinic of a public hospital in Lima, Peru in 2018. High grade SD was the dependent variable, using the IIEF-5 questionnaire and the independent variables were sexual orientation, history of previous pathology, location of tuberculosis, type of treatment scheme and presence of hemoptysis. Prevalence ratios (PR) were estimated using simple and multiple regression models.

RESULTS

Of 189 patients, the majority presented pulmonary tuberculosis (98.9%), overweight (25.9%) and just over half had high-grade ED (52.9%). In the simple regression it was found that the factors associated with presenting high-grade SD were age in years (RP=1.11), reporting diabetes (RP=2.09), having multi-drug resistant TB (RP=1.51) and presenting a treatment time from 1 year to more (RP=1.87). In the multiple regression, the variables that were associated with a higher frequency of high-grade TB were age in years (RP=1.11), a history of diabetes (RP=1.66) and having MDR TB (RP=2.04).

CONCLUSIONS

This study suggests a high prevalence of ED in patients with TB, where four out of ten presented high-grade ED. Being older, having a history of diabetes and using an MDR treatment were positively associated with the development of high-grade ED. Studies with designs close to causality are required to know the real magnitude of the influence of clinical and therapeutic characteristics on the development of high-grade ED.

摘要

目的

确定秘鲁利马重度勃起功能障碍(ED)的患病率及相关因素。

材料与方法

2018年在秘鲁利马一家公立医院的门诊治疗的结核病患者中进行分析性横断面研究。使用国际勃起功能指数-5问卷将重度性功能障碍作为因变量,自变量为性取向、既往病史、结核病发病部位、治疗方案类型及咯血情况。采用简单回归模型和多元回归模型估计患病率比值(PR)。

结果

189例患者中,大多数患有肺结核(98.9%)、超重(25.9%),略超过半数患有重度ED(52.9%)。在简单回归中发现,与出现重度性功能障碍相关的因素有年龄(PR=1.11)、报告患有糖尿病(PR=2.09)、患有耐多药结核病(PR=1.51)以及治疗时间为1年及以上(PR=1.87)。在多元回归中,与重度结核病发生率较高相关的变量有年龄(PR=1.11)、糖尿病史(PR=1.66)和耐多药结核病(PR=2.04)。

结论

本研究表明结核病患者中ED患病率较高,十分之四的患者患有重度ED。年龄较大、有糖尿病史和采用耐多药治疗与重度ED的发生呈正相关。需要开展接近因果关系设计的研究,以了解临床和治疗特征对重度ED发生影响的实际程度。

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