Murdoch University, College of Science, Health, Education & Engineering, Perth, Western Australia, Australia.
Notre Dame University, Fremantle, Australia.
Eur J Pain. 2021 Nov;25(10):2155-2165. doi: 10.1002/ejp.1828. Epub 2021 Jul 19.
Back pain (BP) experienced by females during adolescent years appears to predispose them to an increased likelihood of its presence in adulthood. Understanding this phenomenon by identifying risk factors of those at risk potentially fosters preventative strategies and effective treatments.
To investigate for associations between post-menarche BP and low back pain (LBP) and age at menarche (AAM) in Australian adolescents using the Western Australian pregnancy cohort (The Raine Study).
This study used data from a longitudinal cohort study. BP data were collected retrospectively using a questionnaire. Menarche data was split into three established age classifications early (<12-years), normal (≥12 to >14-years) and late (≥14-years). Logistic regression models examined the effect of AAM on BP.
666 female participants provided valid menarche data with 183 (27.5%) early AAM, 429 (64.4%) normal AAM and 54 (8.1%) with late AAM. The mean AAM was 12.59 years. BP was disclosed by 27.5% in the 14-year follow-up and 31.5% in the 17-year follow-up. Participants who had early AAM had 79% higher odds of experiencing BP compared to participants who had normal AAM, after adjusting for confounders at the 14-year follow-up (adjOR 1.79, 95% CI 1.18-2.64).
There is evidence of an association, in this cohort, of early AAM with post-menarche BP. This result identifies an area for future exploration, including understanding this mechanism which may lead to the development of effective intervention measures.
Age at menarche is related to a range of health issues. This study sought to investigate if it was a risk factor for spinal pain. We used an existing Australian data base to explore this possibility and found an association with early age onset and post-menarche back pain. This result identifies an area for future exploration, including understanding this mechanism which may lead to the development of effective intervention measures.
女性在青少年时期经历的背痛（BP）似乎使她们成年后患背痛的可能性增加。通过确定有风险的人的风险因素来理解这一现象，可能会促进预防策略和有效的治疗。
使用西澳大利亚妊娠队列（Raine 研究）调查澳大利亚青少年月经初潮后 BP 和下腰痛（LBP）与月经初潮年龄（AAM）之间的相关性。
本研究使用了一项纵向队列研究的数据。BP 数据通过问卷调查进行回顾性收集。月经初潮数据分为三个已建立的年龄分类：早期（<12 岁）、正常（≥12 至>14 岁）和晚期（≥14 岁）。逻辑回归模型检查了 AAM 对 BP 的影响。
666 名女性提供了有效的月经初潮数据，其中 183 名（27.5%）初潮年龄较早，429 名（64.4%）初潮年龄正常，54 名（8.1%）初潮年龄较晚。平均 AAM 为 12.59 岁。在 14 年随访时，27.5%的人报告有 BP，在 17 年随访时，31.5%的人报告有 BP。在调整了 14 年随访时的混杂因素后，早期 AAM 的参与者发生 BP 的可能性比正常 AAM 的参与者高 79%（调整后的优势比 1.79，95%CI 1.18-2.64）。
在本队列中，初潮年龄与月经初潮后 BP 之间存在关联的证据。这一结果为未来的研究提供了一个方向，包括了解这一机制，这可能导致有效的干预措施的发展。
月经初潮年龄与一系列健康问题有关。本研究旨在探讨其是否是脊柱疼痛的危险因素。我们使用现有的澳大利亚数据库来探讨这种可能性，发现与初潮年龄早和月经初潮后腰痛之间存在关联。这一结果为未来的研究提供了一个方向，包括了解这一机制，这可能导致有效的干预措施的发展。
