Elshahawy Ibrahim I, Elshanat Sherif, Arab Mayo Mahamat, Nayel Mohamed, Salama Akram, El-Sify Ahmed, Aly Mahmoud
Department of Animal Medicine, Faculty of Veterinary Medicine, Alexandria University, Egypt.
Department of Parasitology, Faculty of Veterinary Medicine, Alexandria University, Egypt.
Vet World. 2021 May;14(5):1153-1157. doi: 10.14202/vetworld.2021.1153-1157. Epub 2021 May 12.
Fasciolosis is a cosmopolitan parasitic disease of food-producing animals and is typically caused by digenetic trematodes, and . It has a direct negative impact on the liver and consequently affects liver metabolism. It has indirect effects, including lowered milk production and effects on quality and general health conditions leading to extensive economic losses. This study aimed to focus on the link between clinical fasciolosis and some biochemical analysis of the hepatic profile of cattle in Chad.
This study was initiated in response to emerging complaints from dairy cattle owners detecting a bitter milk cream and butter taste. Furthermore, those animals had shown poor health conditions by presenting with diarrhea. Preliminary surveillance for possible causes was performed, including fecal and serum biochemical analyses and clinical observation to diagnose the possible disease.
The results obtained, including the finding of parasite stages during the coprological examination, confirmed the role of fasciolosis. The independent sample t-test indicated highly significantly altered values of all biochemical liver indicators in the infected animals. All animals were treated with two doses of rafoxanide (3 mg/kg b.w.) S/C, at 21 days intervals, with vitamin supplements, mineral mixtures, and food additives. Surprisingly, the main complaint was restored after treatment. This is another evident clue of fasciolosis. To the best of our knowledge, this is the first recent study that diagnosed fasciolosis in Chad.
This study emphasized the importance of fasciolosis, its negative impact on milk taste, and the necessity for veterinary advice regarding routine examination and prophylactic measures, especially before autumn, to minimize economic losses. However, regardless of the small sample size, this study could serve as a cornerstone for future studies on evaluating the accurate epidemiological status of fasciolosis in Chad. This study reported a close association between the alteration of liver enzymes and total protein levels in fasciolosis and the bitter milk cream taste, which could be used as a diagnostic tool for fasciolosis.
肝片吸虫病是一种在全球范围内影响食用动物的寄生虫病，通常由双殖吸虫引起。它会对肝脏产生直接负面影响，进而影响肝脏代谢。它还具有间接影响，包括产奶量降低以及对牛奶质量和动物总体健康状况的影响，从而导致巨大的经济损失。本研究旨在聚焦乍得临床肝片吸虫病与牛肝脏生化指标分析之间的联系。
本研究是应奶牛养殖户新出现的投诉而开展的，他们发现牛奶、奶油和黄油有苦味。此外，这些动物还出现腹泻，健康状况不佳。对可能的病因进行了初步监测，包括粪便和血清生化分析以及临床观察，以诊断可能的疾病。
所获得的结果，包括在粪便检查中发现寄生虫阶段，证实了肝片吸虫病的作用。独立样本t检验表明，感染动物的所有肝脏生化指标值均有极显著变化。所有动物每隔21天皮下注射两剂硝碘酚腈（3毫克/千克体重），并补充维生素、矿物质混合物和食品添加剂。令人惊讶的是，治疗后主要投诉的问题得到了解决。这是肝片吸虫病的另一个明显线索。据我们所知，这是乍得最近首次诊断肝片吸虫病的研究。
本研究强调了肝片吸虫病的重要性、其对牛奶味道的负面影响，以及就常规检查和预防措施寻求兽医建议的必要性，尤其是在秋季之前，以尽量减少经济损失。然而，尽管样本量较小，本研究可为未来评估乍得肝片吸虫病准确流行病学状况的研究奠定基础。本研究报告了肝片吸虫病中肝酶和总蛋白水平的变化与牛奶、奶油苦味之间的密切关联，这可作为肝片吸虫病的诊断工具。
