Krain L S, Levin J M, Schultz B
Cutis. 1978 Jan;21(1):80-4.
Immunologic and immunofluorescent profiles of two patients with the Gardner-Diamond syndrome are described. During the time ecchymoses were present, both patients had decreased serum complement levels; when the lesions healed, the serum complement level returned to normal. One patient had associated angioimmunoblastic lymphadenopathy and subepidermal deposits of immunoglobulin IgM at the basement membrane of ecchymotic skin. The other patient had a normal immunofluorescent pattern. Both patients had increased B-cell counts. The association of immunologic and immunofluorescent findings in patients with the Gardner-Diamond syndrome is suggestive and deserves further study.
描述了两名加德纳-戴蒙德综合征患者的免疫学和免疫荧光特征。在出现瘀斑期间，两名患者的血清补体水平均降低；当皮损愈合时，血清补体水平恢复正常。一名患者伴有血管免疫母细胞性淋巴结病，瘀斑皮肤的基底膜有免疫球蛋白IgM的表皮下沉积。另一名患者的免疫荧光模式正常。两名患者的B细胞计数均增加。加德纳-戴蒙德综合征患者免疫学和免疫荧光检查结果之间的关联具有提示意义，值得进一步研究。
