西咪替丁治疗消化性溃疡的住院治疗。II. 胃溃疡患者的对照双盲试验（作者译）
[In-patient treatment of peptic ulcer with cimetidine. II. Controlled double-blind trial on gastric ulcer patients (author's transl)].
作者信息
Sewing K F, Malchow H, Albinus M, Horn B, Schomerus H, Dölle W
出版信息
Dtsch Med Wochenschr. 1978 Jan 27;103(4):152-4. doi: 10.1055/s-0028-1104398.
PMID:342218
Abstract
In a controlled double-blind clinical trial of 39 in-patients with gastric ulcer the effect of cimetidine on ulcer healing, ulcer pain and pentagastrin-stimulated acid and pepsin secretion was measured. A faster healing rate in the cimetidine group was statistically not significant. Cimetidine had no effect on ulcer pain and pentagastrin-stimulated acid and pepsin secretion. There were no serious untoward reactions.
摘要
在一项针对39名胃溃疡住院患者的对照双盲临床试验中，测定了西咪替丁对溃疡愈合、溃疡疼痛以及五肽胃泌素刺激的胃酸和胃蛋白酶分泌的影响。西咪替丁组更快的愈合率在统计学上无显著意义。西咪替丁对溃疡疼痛以及五肽胃泌素刺激的胃酸和胃蛋白酶分泌没有影响。未出现严重不良反应。
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