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J Cancer Res Clin Oncol. 2021 Jul;147(7):2137-2144. doi: 10.1007/s00432-020-03500-7. Epub 2021 Jan 2.
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Sclerodermalike syndromes: Great imitators.硬皮病样综合征:模仿大师。
Clin Dermatol. 2020 Mar-Apr;38(2):235-249. doi: 10.1016/j.clindermatol.2019.10.010. Epub 2019 Oct 24.
3
Esophagectomy for the patients with squamous cell carcinoma of the esophagus after allogeneic hematopoietic stem cell transplantation.异基因造血干细胞移植后食管鳞癌患者的食管切除术。
Int J Clin Oncol. 2020 Jan;25(1):82-88. doi: 10.1007/s10147-019-01549-0. Epub 2019 Sep 23.
4
Clinicopathologic characteristics of secondary squamous cell carcinoma of head and neck in survivors of allogeneic hematopoietic stem cell transplantation for hematologic malignancies.异基因造血干细胞移植治疗血液系统恶性肿瘤后发生的头颈部继发性鳞状细胞癌的临床病理特征。
Bone Marrow Transplant. 2019 Apr;54(4):560-566. doi: 10.1038/s41409-018-0299-x. Epub 2018 Aug 20.
5
Outcomes of patients who developed subsequent solid cancer after hematopoietic cell transplantation.造血细胞移植后发生继发实体瘤的患者结局。
Blood Adv. 2018 Aug 14;2(15):1901-1913. doi: 10.1182/bloodadvances.2018020966.
6
Second Malignancies after Hematopoietic Stem Cell Transplantation.造血干细胞移植后的第二恶性肿瘤。
Curr Treat Options Oncol. 2018 Feb 8;19(2):9. doi: 10.1007/s11864-018-0528-y.
7
Classification systems for chronic graft-versus-host disease.慢性移植物抗宿主病的分类系统。
Blood. 2017 Jan 5;129(1):30-37. doi: 10.1182/blood-2016-07-686642. Epub 2016 Nov 7.
8
High-dose radiation therapy alone by moderate hypofractionation for patients with thoracic esophageal squamous cell carcinoma.单纯大剂量放疗联合适度低分割放疗用于胸段食管鳞状细胞癌患者
Medicine (Baltimore). 2016 Aug;95(33):e4591. doi: 10.1097/MD.0000000000004591.
9
Long-term complications of definitive chemoradiotherapy for esophageal cancer using the classical method.采用经典方法对食管癌进行根治性放化疗的长期并发症。
J Radiat Res. 2017 Jan;58(1):106-113. doi: 10.1093/jrr/rrw078. Epub 2016 Jul 29.
10
Continuing increased risk of oral/esophageal cancer after allogeneic hematopoietic stem cell transplantation in adults in association with chronic graft-versus-host disease.成人异基因造血干细胞移植后慢性移植物抗宿主病与口腔/食管癌风险持续增加相关。
Ann Oncol. 2014 Feb;25(2):435-41. doi: 10.1093/annonc/mdt558. Epub 2014 Jan 7.

异基因造血干细胞移植术后继发性食管癌的根治性放疗

Definitive radiotherapy for secondary esophageal cancer after allogeneic hematopoietic stem cell transplantation.

作者信息

Ino Aki, Sakanaka Katsuyuki, Inoo Hiroyuki, Ishida Yuichi, Kanda Junya, Mizowaki Takashi

机构信息

Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507 Japan.

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507 Japan.

出版信息

Int Cancer Conf J. 2021 Mar 20;10(3):201-206. doi: 10.1007/s13691-021-00479-x. eCollection 2021 Jul.

DOI:10.1007/s13691-021-00479-x
PMID:34221832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8206320/
Abstract

The reports for secondary esophageal cancer treated by radiotherapy or chemoradiotherapy is few, however they potentially yield a cure for esophageal cancer. We report a case of definitive radiotherapy for a patient with secondary locally advanced unresectable esophageal cancer after hematopoietic stem cell transplantation for acute myeloid leukemia. Definitive radiotherapy for the current patient was completed with acceptable toxicity despite the poor general condition with long-term chronic graft-versus-host disease. Radiotherapy may be the definitive treatment for this population unfit for concurrent chemotherapy or surgery.

摘要

关于放疗或放化疗治疗继发性食管癌的报道较少,然而它们有可能治愈食管癌。我们报告一例急性髓系白血病造血干细胞移植后发生继发性局部晚期不可切除食管癌患者的根治性放疗病例。尽管该患者因长期慢性移植物抗宿主病导致全身状况较差,但仍以可接受的毒性完成了根治性放疗。对于不适合同步化疗或手术的这类患者,放疗可能是根治性治疗方法。