Ozdemir Oner
Division of Allergy and Immunology, Department of Pediatrics, Sakarya University Faculty of Medicine, Training and Research Hospital, Sakarya, Turkey.
North Clin Istanb. 2021 Apr 29;8(3):275-279. doi: 10.14744/nci.2020.46656. eCollection 2021.
When applied by well-trained personnel, skin prick test (SPT) for a variety of inhalant and/or food allergens is a safe procedure although it may rarely cause systemic reaction. In this article, our aim was to evaluate the reactions after SPTs for the past 6 years in Turkish children having various allergic symptoms brought to our clinic.
The results of the SPTs, performed between May 2013 and March 2019, of 12.529 patients whose ages vary from 2 months to 18 years have been retrospectively evaluated.
The average age of the patients who were included in this study was 6.12±4.38 years and 46.4% of them were female. When the patients were categorized according to the diagnosis, it was observed that 4.858 of them with symptoms suggesting asthma; 2.720 of them having symptoms suggesting allergic rhinitis; 1.795 of them having rashes; 906 of them with atopic dermatitis; 352 of them having symptoms suggesting food allergy and the remaining 1.898 with symptoms suggesting various diagnoses. In this study, which reflects our 6-year experience from the results of 12.529 patients, post-SPT reactions have been observed in 9 out of 12.529 patients (0.07%). They were three females and six males. These reactions were observed in 3 eczemas, 2 urticaria, 2 allergic rhinitis, and 2 suggested diagnosis of asthma patients. Their mean age was 5.9±3.5 years. SPT reactions were mostly seen in our five patients having skin disorder (eczema and rashes). The most frequent symptom of vasovagal reaction was syncope, occuring between 1 and 20 min after SPT, in eight of nine patients.
During our study, any systemic reaction or anaphylaxis to SPT was not observed. The non-systemic reaction (vasovagal reaction) rate was 7/10.000, similar to the literature.
由训练有素的人员进行操作时，针对多种吸入性和/或食物过敏原的皮肤点刺试验（SPT）是一种安全的检查方法，尽管它很少会引起全身反应。在本文中，我们的目的是评估过去6年里因各种过敏症状前来我们诊所就诊的土耳其儿童在进行皮肤点刺试验后的反应。
对2013年5月至2019年3月期间对年龄从2个月至18岁的12529例患者进行的皮肤点刺试验结果进行回顾性评估。
纳入本研究的患者平均年龄为6.12±4.38岁，其中46.4%为女性。根据诊断对患者进行分类时，发现其中4858例有提示哮喘的症状；2720例有提示过敏性鼻炎的症状；1795例有皮疹；906例有特应性皮炎；352例有提示食物过敏的症状，其余1898例有提示各种诊断的症状。在这项反映我们对12529例患者6年经验的研究中，12529例患者中有9例（0.07%）观察到皮肤点刺试验后出现反应。他们中3例为女性，6例为男性。这些反应出现在3例湿疹、2例荨麻疹、2例过敏性鼻炎以及2例提示哮喘诊断的患者中。他们的平均年龄为5.9±3.5岁。皮肤点刺试验反应大多出现在我们5例有皮肤疾病（湿疹和皮疹）的患者中。血管迷走性反应最常见的症状是晕厥，在9例患者中有8例在皮肤点刺试验后1至20分钟内发生。
在我们的研究过程中，未观察到对皮肤点刺试验的任何全身反应或过敏反应。非全身反应（血管迷走性反应）发生率为万分之七，与文献报道相似。
