Pais Riona, Lee Philip, Cross Shamira, Gebski Val, Aggarwal Rajesh
Department of Palliative Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Department of Supportive and Palliative Medicine, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia.
Palliat Med Rep. 2020 Oct 30;1(1):251-258. doi: 10.1089/pmr.2020.0060. eCollection 2020.
Urinary catheterization is often undertaken to relieve distressing bladder symptoms in palliative care. The primary aim of this study was to determine the incidence of, and clinical indications that predispose patients admitted to palliative care units to, urinary catheterization. The secondary aims were to determine causal factors, including the type of malignancy, antecedent medications, and duration of admission in these patients. This was a prospective observational dual site cohort study in palliative care inpatients. Univariate categorical chi-square analysis was performed to compare patients with and without urinary catheterization, and to identify risk factors associated with urinary catheter use. The incidence of catheterization in this cohort was 41% (43/104) and urinary retention (63%) was the most common cause. Agitation (47%) and urinary incontinence (70%) were common symptoms in those catheterized. Medications that were significantly associated with the need for urinary catheterization were benzodiazepines ( < 0.01) and antipsychotics ( = 0.01). All measures that define poor functional status were found to be significant ( < 0.01). Patients with prolonged hospitalization of greater than three weeks were catheterized more frequently ( = 0.017). The majority of patients catheterized (79%) were admitted for terminal care. The high incidence of urinary catheterization highlights the need for good bladder care for all patients in the palliative care setting. Patients with risk factors include the use of antipsychotics and benzodiazepines, declining functional status and prolonged hospital admission are more likely to be catheterized.
在姑息治疗中,导尿术常用于缓解令人痛苦的膀胱症状。本研究的主要目的是确定姑息治疗病房收治患者的导尿发生率及易导致导尿的临床指征。次要目的是确定这些患者的因果因素,包括恶性肿瘤类型、先前用药情况及住院时间。这是一项针对姑息治疗住院患者的前瞻性观察性双中心队列研究。采用单变量分类卡方分析比较导尿和未导尿患者,并确定与导尿使用相关的危险因素。该队列中的导尿发生率为41%(43/104),尿潴留(63%)是最常见原因。导尿患者中常见的症状是烦躁(47%)和尿失禁(70%)。与导尿需求显著相关的药物是苯二氮䓬类药物(<0.01)和抗精神病药物(=0.01)。所有定义功能状态差的指标均具有显著性(<0.01)。住院时间超过三周的患者导尿频率更高(=0.017)。大多数导尿患者(79%)因终末期护理入院。导尿的高发生率凸显了在姑息治疗环境中对所有患者进行良好膀胱护理的必要性。有危险因素的患者,包括使用抗精神病药物和苯二氮䓬类药物、功能状态下降以及住院时间延长,更有可能接受导尿。