Lapointe H J, Listrom R
University of Toronto.
Oral Surg Oral Med Oral Pathol. 1988 Jan;65(1):76-80. doi: 10.1016/0030-4220(88)90196-x.
Oxalosis is a rare condition that may be either hereditary or acquired. It may be secondary to a number of primary causes, which include renal failure, oxalate poisoning, malabsorption syndromes, and in this case, ileojejunal bypass surgery. Systemic oxalate overload following such bypass surgery results from a defect in the enterohepatic circulation and from the loss of calcium and bile salts in the feces. The oxalate is then absorbed into the circulation, and the supersaturated solution precipitates in the systemic tissues. Reported cases of oral involvement are rare. This article presents a 2 1/2-year follow-up of such a patient and the resultant progressive and unrelenting nature of the disorder. As a result of our experience, we suggest early aggressive oral surgical management of the widespread oral lesions.
草酸盐沉着症是一种罕见的病症,可能是遗传性的,也可能是后天获得的。它可能继发于多种原发性病因,包括肾衰竭、草酸盐中毒、吸收不良综合征,在本病例中还包括回肠空肠旁路手术。此类旁路手术后的全身性草酸盐过载是由于肠肝循环缺陷以及粪便中钙和胆汁盐的流失所致。然后草酸盐被吸收进入循环系统,过饱和溶液在全身组织中沉淀。报道的口腔受累病例很少见。本文介绍了一名此类患者的2年半随访情况以及该病症持续进展且无法缓解的特性。基于我们的经验,我们建议对广泛的口腔病变尽早采取积极的口腔外科治疗。