Kim Eon Su, Yang Chae Eun, Chung Yoon Kyu
Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Arch Craniofac Surg. 2021 Jun;22(3):135-140. doi: 10.7181/acfs.2021.00206. Epub 2021 Jun 25.
Wide surgical excision is the gold standard for basal cell carcinoma (BCC) treatment. Typically, resection requires a safety margin ≥ 4 mm. We aimed to confirm BCC excisions' cancer recurrence rate and safety on the facial region with new safety margins.
We included patients with primary BCC on the facial region who underwent wide excision with 2- or 3-mm safety margins at our institution between January 2010 and December 2018. Medical records were reviewed to confirm the epidemiology and surgical information. Recurrence was confirmed by physical examination through regular 6-month follow-up.
We included 184 out of 233 patients in this study after applying the exclusion criteria. The mean age and follow-up period were 71.2± 10.2 years and 29.3± 13.5 months, respectively. The predominantly affected area was the nose (95 cases); a V-Y advancement flap was the most commonly used surgical method. There were two cases of recurrence in the 2 mm margin group and one recurrence in the group resected with 3 mm margins.
In this large cohort study, we found 2-3 mm excision margins can yield enough safety in facial BCCs. The recurrence rates were found to be comparable with those reported after wider margins.
广泛手术切除是基底细胞癌（BCC）治疗的金标准。通常，切除需要≥4mm的安全切缘。我们旨在确定采用新的安全切缘对面部区域进行BCC切除后的癌症复发率及安全性。
我们纳入了2010年1月至2018年12月期间在我院接受2mm或3mm安全切缘广泛切除的面部原发性BCC患者。查阅病历以确认流行病学及手术信息。通过定期6个月随访的体格检查确认复发情况。
应用排除标准后，本研究纳入了233例患者中的184例。平均年龄和随访时间分别为71.2±10.2岁和29.3±13.5个月。主要受累部位为鼻子（95例）；V-Y推进皮瓣是最常用的手术方法。2mm切缘组有2例复发，3mm切缘切除组有1例复发。
在这项大型队列研究中，我们发现2 - 3mm的切除切缘对面部BCC可产生足够的安全性。发现复发率与更宽切缘切除后报道的复发率相当。
