催产素和加压素在社会行为中的性别差异。
Sex differences of oxytocin and vasopressin in social behaviors.
机构信息
Department of Psychiatry, Hangzhou Seventh People's Hospital, Hangzhou, China.
Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; The Key Laboratory of Mental Disorder Management in Zhejiang Province, Hangzhou, China; Brain Research Institute of Zhejiang University, Hangzhou, China.
出版信息
Handb Clin Neurol. 2021;180:65-88. doi: 10.1016/B978-0-12-820107-7.00005-7.
The neuropeptides oxytocin (OT) and vasopressin (VP) are known to mediate social cognition and behaviors in a sex-dependent manner. This chapter reviews the sex-dependent influence of OT and VP on social behaviors, focusing on (1) partner preference and sexual orientation, (2) memory modulation, (3) emotion regulation, and (4) trust-related behaviors. Most studies suggest that OT promotes familiar (opposite-sex) partner preference, strengthens memory, relieves anxiety, and increases trust. However, VP-regulated social cognition has been studied less than OT. VP facilitates familiar (opposite-sex) partner preference, enhances memory, induces anxiety, and influences happiness/anger perception. Detailed sex differences of these effects are reviewed. There is a male preponderance in the use of animal models and many study results are too complex to draw firm conclusions. Clarifying the complex interplay between the OT/VP system and sex hormones in the regulation of social behaviors is needed.
神经肽催产素（OT）和血管升压素（VP）已知以性别依赖的方式介导社会认知和行为。本章综述了 OT 和 VP 对社会行为的性别依赖性影响，重点关注（1）伴侣偏好和性取向，（2）记忆调节，（3）情绪调节，以及（4）信任相关行为。大多数研究表明，OT 促进熟悉（异性）伴侣偏好，增强记忆，缓解焦虑，增加信任。然而，VP 调节的社会认知研究比 OT 少。VP 促进熟悉（异性）伴侣偏好，增强记忆，引起焦虑，并影响幸福感/愤怒感知。综述了这些影响的详细性别差异。在动物模型的使用中存在男性优势，并且许多研究结果过于复杂，无法得出明确的结论。需要阐明 OT/VP 系统与性激素在调节社会行为中的复杂相互作用。
Zotero 插件