一种稳定的DNA-蛋白质复合物的代谢行为。
Metabolic behaviour of a stable DNA-protein complex.
作者信息
Avramova Z, Mikhailov I, Tsanev R
机构信息
Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia.
出版信息
Int J Biochem. 1988;20(1):61-5. doi: 10.1016/0020-711x(88)90011-0.
PMID:3422630
Abstract
- A stable DNA-protein complex resisting all treatments dissociating noncovalently associated proteins was isolated from mouse erythroleukemia cells. 2. Two-dimensional tryptic peptide mapping of this DNA-linked protein component revealed a remarkable similarity to the maps of the corresponding proteins from other mammalian chromatins. 3. Labelling experiments showed that the protein component was metabolically stable.
摘要
- 从小鼠红白血病细胞中分离出一种稳定的DNA-蛋白质复合物，该复合物能抵抗所有解离非共价结合蛋白质的处理。2. 对这种与DNA相连的蛋白质成分进行二维胰蛋白酶肽图谱分析，结果显示它与其他哺乳动物染色质中相应蛋白质的图谱有显著相似性。3. 标记实验表明该蛋白质成分在代谢上是稳定的。
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