Division of Infectious Diseases and Geographic Medicine, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Curr Opin Infect Dis. 2021 Aug 1;34(4):372-383. doi: 10.1097/QCO.0000000000000734.
An estimated four to 11% of reported coronavirus disease 2019 (COVID-19) cases occurs in healthcare personnel (HCP). HCP are at high risk of acquiring and transmitting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) given their close contact with individuals with recognized and unrecognized COVID-19. We summarize the literature to date describing the epidemiology, identifying risk factors associated with COVID-19, and analyzing clinical characteristics and outcomes of SARS-CoV-2 infection in HCP.
The prevalence of SARS-CoV-2 antibodies among HCP ranges from 0.7 to 45%. Although there is heterogeneity in the seroprevalence rate reported in the literature, HCP may be at increased risk of SARS-CoV-2 infection from exposure to patients with COVID-19. The literature supports that this can be minimized with adequate personal protective equipment (PPE) supply, proper hand hygiene, appropriate PPE use, and other infection prevention measures. In addition, infections in HCP are commonly acquired in the community as well as in nonclinical care settings including break rooms or work rooms.
While much focus has been on minimizing patient-to-HCP transmission of SARS-CoV-2, additional efforts are needed to prevent exposures in nonclinical care settings and in the community.
据报道,在报告的 COVID-19 病例中,有 4%至 11%发生在医护人员(HCP)中。由于 HCP 与确诊和未确诊 COVID-19 的患者密切接触,因此他们感染和传播严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的风险很高。我们总结了迄今为止描述 COVID-19 流行病学、确定与 COVID-19 相关的危险因素以及分析 SARS-CoV-2 感染在 HCP 中的临床特征和结局的文献。
HCP 中 SARS-CoV-2 抗体的流行率范围为 0.7%至 45%。尽管文献中报告的血清阳性率存在异质性,但 HCP 由于接触 COVID-19 患者,可能面临 SARS-CoV-2 感染的风险增加。文献支持,通过提供足够的个人防护设备(PPE)、适当的手部卫生、正确使用 PPE 和其他感染预防措施,可以将这种风险降到最低。此外,HCP 的感染通常发生在社区以及非临床护理环境中,包括休息室或工作间。
虽然人们一直致力于将 SARS-CoV-2 从患者传播到 HCP 的风险降到最低,但还需要做出额外的努力来预防非临床护理环境和社区中的暴露。