Dubrovskaia V F, Gubareva A V
Radiobiologiia. 1987 Nov-Dec;27(6):793-6.
A comparative study was conducted on the development of a remote radiation pathology in rat lungs after single local irradiation with doses of 10, 14.3 and 20 Gy in the air, and 14.3 and 20 Gy in a gas hypoxic mixture containing 10 per cent of oxygen. From the morphological evaluation of the dynamics and the degree of pneumosclerosis manifestations at different times following irradiation the protective effect of gas hypoxic mixture was evident whose value, as estimated by the accretion of the connective tissue in the exposed lung, was a function of radiation dose.
对大鼠肺部进行了一项对比研究,研究内容为在空气中分别给予10、14.3和20 Gy剂量的单次局部照射后,以及在含10%氧气的气体低氧混合物中给予14.3和20 Gy剂量的单次局部照射后,大鼠肺部远程辐射病理学的发展情况。通过对照射后不同时间肺硬化表现的动态变化和程度进行形态学评估,发现气体低氧混合物具有明显的保护作用,根据照射肺中结缔组织的增生情况估计,其保护作用的大小是辐射剂量的函数。