推测与严重急性呼吸综合征冠状病毒2诱导的狼疮抗凝物相关的视网膜中央静脉阻塞
Central Retinal Vein Occlusion Presumably Associated with Lupus Anticoagulant Induced by SARSCoV-2.
作者信息
Cuadros Sánchez Carlos, Egüen Cristina Sacristán, Gutierrez-Ezquerro Raquel, Giralt-Peret Lena, Fonollosa Alex
机构信息
Department of Ophthalmology, BioCruces Bizkaia Health Research Institute, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Department of Ophthalmology, University Torrevieja Hospital, Torrevieja, Alicante, España.
出版信息
Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):2010-2013. doi: 10.1080/09273948.2021.1933077. Epub 2021 Jul 8.
PURPOSE
To report a case of unilateral central retinal vein occlusion (CRVO) and macular edema presumably associated with lupus anticoagulant (LA) induced by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2).
METHOD
Case report.
RESULTS
A 32-year-old male patient presented to the emergency department with a 5-day history of blurry vision. He was diagnosed with a CRVO and macular edema. The only pathological finding was positive LA which could have been induced by his recent confirmed SARS CoV-2 infection. The patient's evolution was satisfactory after two injections of Intravitreal dexamethasone (Ozurdex®), with improvement in macular edema and visual acuity.
CONCLUSION
COVID-19 may be associated to retinal vascular occlusive disorders. Transient virus-induced LA might play a role in the pathogenesis of the thrombotic event.
目的
报告一例单侧视网膜中央静脉阻塞（CRVO）和黄斑水肿病例，推测其与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）诱导的狼疮抗凝物（LA）有关。
方法
病例报告。
结果
一名32岁男性患者因视力模糊5天就诊于急诊科。他被诊断为CRVO和黄斑水肿。唯一的病理发现是LA阳性，这可能是由他最近确诊的SARS-CoV-2感染引起的。患者在两次玻璃体内注射地塞米松（Ozurdex®）后病情进展良好，黄斑水肿和视力均有改善。
结论
2019冠状病毒病（COVID-19）可能与视网膜血管阻塞性疾病有关。短暂的病毒诱导LA可能在血栓形成事件的发病机制中起作用。
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