Department of Cardiovascular Surgery, Erciyes University School of Medicine, Kayseri, Turkey.
Braz J Cardiovasc Surg. 2022 Aug 16;37(4):517-524. doi: 10.21470/1678-9741-2020-0542.
In this study, we aimed to investigate the relationship between postoperative mortality, morbidity, hospital stay and development of postoperative complications with the glycosylated hemoglobin (HbA1c) level and low left ventricular ejection fraction (LVEF) in diabetic and non-diabetic patients who underwent elective coronary artery bypass (CABG) surgery.
The medical records of patients who underwent CABG at our clinic between January 2015 and December 2019 were retrospectively analyzed. All patients were divided into two groups according to their diabetes mellitus (DM) diagnosis. Diabetic patients were also divided into two groups according to their HbA1c levels. The HbA1c threshold value was 7%. All patients were divided into two groups in terms of LVEF. The LVEF threshold value was 40%.
We analyzed 393 patients, of which 304 (77.4%) were male and 177 (45.04%) patients were diabetic. For lower LVEF and HbA1c values, we found no relationship between postoperative mortality, prolonged intensive care unit (ICU) stay and development of postoperative complications. Deep surgical site infection (DSSI) was found to be more common in diabetic patients who had a higher HbA1c value. Length of hospital stay was longer in diabetic patients with HbA1c levels <7%.
No statistically significant relationship was found between LVEF and HbA1c levels and postoperative mortality, prolonged ICU stay and postoperative complications.
在这项研究中,我们旨在探讨糖化血红蛋白(HbA1c)水平和左心室射血分数(LVEF)低下与接受择期冠状动脉旁路移植术(CABG)的糖尿病和非糖尿病患者的术后死亡率、发病率、住院时间和术后并发症发展之间的关系。
回顾性分析了 2015 年 1 月至 2019 年 12 月在我们诊所接受 CABG 的患者的病历。所有患者根据糖尿病(DM)诊断分为两组。根据 HbA1c 水平,糖尿病患者也分为两组。HbA1c 阈值为 7%。根据 LVEF 将所有患者分为两组。LVEF 阈值为 40%。
我们分析了 393 名患者,其中 304 名(77.4%)为男性,177 名(45.04%)为糖尿病患者。对于较低的 LVEF 和 HbA1c 值,我们发现术后死亡率、延长重症监护病房(ICU)停留时间和术后并发症的发展之间没有关系。我们发现,HbA1c 值较高的糖尿病患者更易发生深部手术部位感染(DSSI)。HbA1c 水平<7%的糖尿病患者的住院时间更长。
LVEF 和 HbA1c 水平与术后死亡率、延长 ICU 停留时间和术后并发症之间没有统计学上的显著关系。