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糖化血红蛋白作为沙特人群冠状动脉搭桥手术后患者住院时间的预测指标

Glycated Hemoglobin as a Predictor of the Length of Hospital Stay in Patients Following Coronary Bypass Graft Surgery in the Saudi Population.

作者信息

Almogati Joud G, Ahmed Elnazeer O

机构信息

Faculty of Medicine, King Abdulaziz University, Kingdom of Saudi Arabia.

Cardiac Surgery Department, King Abdullah Medical City, Makkah, Kingdom of Saudi Arabia.

出版信息

Braz J Cardiovasc Surg. 2019 Jan-Feb;34(1):28-32. doi: 10.21470/1678-9741-2018-0202.

DOI:10.21470/1678-9741-2018-0202
PMID:30810671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6385841/
Abstract

OBJECTIVE

The diabetic population has a high prevalence of coronary artery disease, and frequently patients with diabetes undergo coronary artery bypass graft (CABG) surgery. Elevated glycated hemoglobin (HbA1c) in diabetics is shown to be associated with morbidity and mortality, but the association of HbA1c with postoperative length of hospital stay (LOS) has conflicting results. In this study, we aim to identify if elevated HbA1c levels are associated with prolonged LOS after CABG surgery.

METHODS

A retrospective chart review study was performed, using a total of 305 patients who were referred for CABG surgery. HbA1c levels were measured before the day of surgery. Patients were classified into two groups according to HbA1c levels: <7% and ≥7%. A LOS of more than 14 days was proposed as an extended LOS. HbA1c and the LOS relationship were assessed using appropriate statistical methods.

RESULTS

Patients who had diabetes mellitus comprised 81.6% of our studied population. Sixty-four percent had HbA1c levels ≥ 7%. There was no significant difference in the total LOS in HbA1c <7% compared to HbA1c ≥7% patients (P=0.367).

CONCLUSION

Our study results rejected the proposed hypothesis that elevated HbA1c levels ≥7% would be associated with prolonged hospital stay following CABG surgery in a Saudi population.

摘要

目的

糖尿病患者冠状动脉疾病患病率较高,糖尿病患者常接受冠状动脉旁路移植术(CABG)。糖尿病患者糖化血红蛋白(HbA1c)升高与发病率和死亡率相关,但HbA1c与术后住院时间(LOS)的关系存在矛盾的结果。在本研究中,我们旨在确定HbA1c水平升高是否与CABG术后住院时间延长有关。

方法

进行了一项回顾性图表审查研究,共纳入305例接受CABG手术的患者。在手术前一天测量HbA1c水平。根据HbA1c水平将患者分为两组:<7%和≥7%。将住院时间超过14天定义为延长住院时间。使用适当的统计方法评估HbA1c与住院时间的关系。

结果

糖尿病患者占我们研究人群的81.6%。64%的患者HbA1c水平≥7%。HbA1c<7%的患者与HbA1c≥7%的患者总住院时间无显著差异(P=0.367)。

结论

我们的研究结果否定了以下假设:在沙特人群中,HbA1c水平≥7%升高与CABG术后住院时间延长有关。

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