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马拉维北部卡龙加地区用于癌症治疗的药用植物的民族植物学研究

Ethnobotanical Study of Medicinal Plants Used for Management of Cancer in Karonga District, Northern Malawi.

作者信息

Mwamatope Bonface, Tembo David, Chikowe Ibrahim, Maliwichi-Nyirenda Cecilia, Kampira Elizabeth, Masumbu Friday Foster

机构信息

College of Medicine, University of Malawi, Zomba, Malawi.

Africa Centre of Excellence in Public Health and Herbal Medicine, College of Medicine, University of Malawi, Zomba, Malawi.

出版信息

Anticancer Agents Med Chem. 2022;22(8):1622-1631. doi: 10.2174/1871520621666210708122037.

Abstract

BACKGROUND

In Malawi, cancer is one of the leading causes of morbidity and mortality. This has led to increased use of herbal medicines for cancer management.

OBJECTIVE

This study aimed at identifying medicinal plants that are used for the management of cancer in the southern area of Karonga district, Northern Malawi.

METHODS

Semi-structured individual questionnaire interviews were used to collect ethnobotanical data from traditional herbal practitioners in the study area.

RESULTS

A total of twenty six (26) plant species from seventeen (17) botanical families were reported by Traditional Herbal Practitioners to be effective in the management of cancer. The botanical families with representation of more than one plant species were Fabaceae with five species, followed by Combretaceae and the Anacardiaceae with three species each, and Meliaceaewith with two species. The relative frequency of citation (RFC) showed that Senna singueana (RFC = 0.833), Lannea discolour (RFC = 0.833), Melia azedarach (RFC = 0.667), and Moringa oleifera (RFC = 0.667) were the medicinal plant species which were frequently mentioned and used in the study. The recipes could be a mixture of plant species or plant parts such as the leaves, barks, roots, rhizomes, seeds, flowers, and fruits.

CONCLUSION

The study showed that a potential cancer management drug could be developed from the medicinal plant species found in the area. The results of this study could provide baseline information on medicinal plant species for further phytochemical studies and other studies to validate their use.

摘要

背景

在马拉维,癌症是发病和死亡的主要原因之一。这导致用于癌症治疗的草药使用增加。

目的

本研究旨在确定马拉维北部卡龙加区南部用于治疗癌症的药用植物。

方法

采用半结构化个人问卷调查,从研究区域的传统草药从业者那里收集民族植物学数据。

结果

传统草药从业者报告称,共有来自17个植物科的26种植物对癌症治疗有效。有多种植物的植物科中,豆科有5种,其次是使君子科和漆树科各有3种,楝科有2种。引用相对频率(RFC)显示,森纳单叶豆(RFC = 0.833)、变色厚皮树(RFC = 0.833)、苦楝(RFC = 0.667)和辣木(RFC = 0.667)是研究中经常提及和使用的药用植物物种。配方可以是植物物种或植物部分的混合物,如叶子、树皮、根、根茎、种子、花和果实。

结论

该研究表明,可以从该地区发现的药用植物物种中开发出一种潜在的癌症治疗药物。本研究结果可为进一步的植物化学研究和其他验证其用途的研究提供药用植物物种的基线信息。

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