卡马西平用于治疗单纯疱疹病毒性脑炎的精神后遗症。

Carbamazepine as therapy for psychiatric sequelae of herpes simplex encephalitis.

作者信息

Vallini A D, Burns R L

机构信息

Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Columbia, SC.

出版信息

South Med J. 1987 Dec;80(12):1590-2. doi: 10.1097/00007611-198712000-00026.

DOI:10.1097/00007611-198712000-00026

PMID:3423906

Abstract

We have presented a case of herpes simplex encephalitis that is interesting in that seizure activity was detected in mesial temporal structures, without manifestations of seizure activity except for severe emotional lability with explosive emotional outbursts. Response to carbamazepine (Tegretol) included marked reduction in EEG-detected seizure activity and in the frequency of emotional outbursts, extending to one year after treatment.

摘要

我们报告了一例单纯疱疹病毒性脑炎病例，该病例的有趣之处在于，在颞叶内侧结构中检测到癫痫活动，除了伴有爆发性情绪发作的严重情绪不稳定外，没有癫痫活动的表现。对卡马西平（ Tegretol）的反应包括脑电图检测到的癫痫活动和情绪发作频率显著降低，这种情况一直持续到治疗后一年。