Arikrishnan Dharanipriya, Balakrishnan Thalaivirithan Margabandu, Janardhanam Jaganmohan
Department of Plastic and Faciomaxillary Surgery, Madras Medical College, Chennai, India.
Indian J Plast Surg. 2021 Apr;54(2):177-185. doi: 10.1055/s-0041-1729505. Epub 2021 Jul 5.
"Subfascial void reconstruction" in ischial pressure sores (IPSs) goes a long way in the amelioration of the common complications like persistent drainage, infection, wound dehiscence, and late recurrence. No locoregional flaps suffice this requirement. So we have designed a chimeric pedicled flap based on the inferior gluteal vessel axis (IGVA) perforators with two tissue components: (1) Pacman-style fasciocutaneous flap on a perforator and (2) gluteus maximus muscle (inferior portion) on another independent perforator. After confirming the feasibility of novel design of chimeric pedicled IGVA perforator flap with cadaver study, we embarked on the clinical study with this chimeric flap. In this prospective cohort study, the study and the control existed in the same patient so that the biological factors affecting the wound healing would be the same. Twenty-one patients were included whose mean age was 39 years. Late recurrence occurred in one patient (4.8%) of chimeric flap while the control group (who had undergone conventional reconstruction) had recurrence in 11 patients (52.4%). On assessment with overall institutional score, grade A was observed in 18 patients of the chimeric IGVA flap group ( < 0.045), and in only 3 patients of the control group. This anatomically construed flap, a new addendum in the armamentarium of reconstruction of IPSs, with its potential to congruently fill the ischiogluteal subfascial void may provide a lasting solution for preventing recurrences.
坐骨压力性溃疡(IPS)的“筋膜下间隙重建”在改善诸如持续引流、感染、伤口裂开和晚期复发等常见并发症方面大有帮助。没有局部皮瓣能满足这一需求。因此,我们设计了一种基于臀下血管轴(IGVA)穿支的嵌合带蒂皮瓣,它有两个组织成分:(1)一个穿支上的吃豆人式筋膜皮瓣和(2)另一个独立穿支上的臀大肌(下部)。在通过尸体研究证实了嵌合带蒂IGVA穿支皮瓣新设计的可行性后,我们开始了对这种嵌合皮瓣的临床研究。在这项前瞻性队列研究中,研究组和对照组存在于同一患者体内,这样影响伤口愈合的生物学因素将是相同的。纳入了21例患者,平均年龄为39岁。嵌合皮瓣组有1例患者(4.8%)发生晚期复发,而对照组(接受传统重建)有11例患者(52.4%)复发。根据整体机构评分进行评估,嵌合IGVA皮瓣组的18例患者为A级(<0.045),而对照组只有3例患者为A级。这种根据解剖结构构建的皮瓣是IPS重建工具中的一个新补充,它有可能完全填充坐骨臀肌筋膜下间隙,可能为预防复发提供一个持久的解决方案。