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心脏 CT 扫描未发现亚临床冠状动脉疾病对单次消融术后心房颤动复发的影响。

No impact of sub-clinical coronary artery disease identified by cardiac CT scan on the recurrence of atrial fibrillation after a single ablation procedure.

机构信息

Department of Cardiology, University Hospital Center Dijon-Bourgogne, 14 rue Gaffarel, 21079, Dijon Cedex, France.

Department of Imagery, University Hospital Center Dijon-Bourgogne, Dijon, France.

出版信息

J Interv Card Electrophysiol. 2022 Aug;64(2):393-400. doi: 10.1007/s10840-021-01018-7. Epub 2021 Jul 9.

Abstract

BACKGROUND

Performing a cardiac CT scan before ablation provides a better understanding of the anatomical variations of the left atrium and pulmonary veins, as well as an analysis of coronary anatomy and the calcium score. The aim of the present study was to determine whether the CT characteristics of patients with unknown CAD have an impact on recurrence of AF.

METHODS

This monocentric retrospective study included patients with AF who had undergone cardiac CT prior to a single ablation.

RESULTS

Among the 229 patients included in the study, 70 (30.5%) presented AF recurrence between 3 and 12 months after a single ablation. The prevalence of CAD confirmed by CT coronary angiogram and the coronary calcium score were similar in the two groups. Patients with recurrent atrial fibrillation had a significantly higher LAVI evaluated by CT scan than patients without recurrence. The ROC curve determined an optimal LAVI threshold of 49 mL/m. In multivariate analysis, the LAVI measured by CT scan was independently associated with the risk of AF recurrence.

CONCLUSIONS

Our study confirms that CAD is not a predictor of AF recurrence after a single ablation, unlike the LAVI. Further studies are necessary to re-evaluate the long-term conclusions of this work.

摘要

背景

在消融术之前进行心脏 CT 扫描可以更好地了解左心房和肺静脉的解剖结构变化,以及冠状动脉解剖结构和钙评分的分析。本研究的目的是确定患有未知 CAD 的患者的 CT 特征是否会对 AF 的复发产生影响。

方法

这是一项单中心回顾性研究,纳入了在单次消融术前行心脏 CT 检查的 AF 患者。

结果

在 229 例患者中,有 70 例(30.5%)在单次消融术后 3 至 12 个月内出现 AF 复发。两组患者的 CT 冠状动脉造影和冠状动脉钙评分证实的 CAD 患病率相似。与未复发的患者相比,复发性心房颤动患者的 CT 扫描评估的 LAVI 显著更高。ROC 曲线确定了 49mL/m 的最佳 LAVI 阈值。多变量分析表明,CT 扫描测量的 LAVI 与 AF 复发的风险独立相关。

结论

我们的研究证实,CAD 不是单次消融术后 AF 复发的预测因素,而 LAVI 则不然。需要进一步的研究来重新评估这项工作的长期结论。

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