Cowie R L, King L M
Department of Medicine, Ernest Oppenheimer Hospital, Welkom, OFS.
S Afr Med J. 1987 Dec 19;72(12):849-50.
In a population with a high prevalence of tuberculosis, no statistically significant risk of developing pulmonary tuberculosis could be attributed to the long-term use of systemic corticosteroid therapy in a group of asthmatic men. A trend towards an increased risk of tuberculosis was noted but the extent of the attributable risk was too small to justify routine treatment with isoniazid. There is certainly no justification for withholding necessary corticosteroid therapy in black subjects with asthma.
在结核病高流行率的人群中，对于一组哮喘男性患者，长期使用全身性皮质类固醇疗法并未显示出患肺结核的统计学显著风险。虽注意到结核病风险有增加趋势，但可归因风险程度过小，不足以证明常规使用异烟肼治疗的合理性。对于患有哮喘的黑人患者，当然没有理由不给予必要的皮质类固醇治疗。
