Sharp Mary Birch, Hospital for Women & Newborns, San Diego, CA, USA.
Sharp Neonatal Research Institute, San Diego, CA, USA.
J Perinatol. 2021 Oct;41(10):2395-2407. doi: 10.1038/s41372-021-01139-x. Epub 2021 Jul 9.
Adjuvant respiratory therapies in preterm neonates aim to reduce long-term morbidities and mortality. Commonly utilized therapies include caffeine, systemic glucocorticosteroids, inhaled steroids, inhaled bronchodilators, and diuretics. This review discusses the available literature that supports some of these practices and points out where clinical practices are not corroborated by evidence. Therapies with no proven clinical benefit must be weighed against potential adverse effects.
早产儿辅助呼吸治疗旨在降低长期发病率和死亡率。常用的治疗方法包括咖啡因、全身糖皮质激素、吸入性类固醇、吸入性支气管扩张剂和利尿剂。本文综述了支持这些治疗方法的现有文献，并指出了哪些临床实践没有得到证据的支持。没有临床获益证据的治疗方法必须权衡其潜在的不良反应。
