Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
World Neurosurg. 2021 Dec;156:e1-e8. doi: 10.1016/j.wneu.2021.07.001. Epub 2021 Jul 7.
Dropped head syndrome is a morbid condition that affects daily functionality, causing pain and dysphagia and respiratory compromise. Reported causes of dropped head syndrome include neuromuscular disorders, iatrogenic from cervical spine surgery, and idiopathic and postradiation for head and neck cancers. Management of this spinal disorder remains challenging, as the complication rates are high. We present our series of 7 patients who underwent surgical correction of dropped head syndrome, all resulting from radiation for head and neck cancers.
This was a retrospective review of 7 patients who underwent surgery between 2016 and 2019 for dropped head syndrome secondary to postradiation cervical spine deformity. Clinical variables were obtained from medical records. Radiographic parameters pre- and postsurgery including T1 slope, sagittal vertical axis, and C2-C7 cervical lordosis were examined.
Seven patients were included in the study, with an average age 69 years. Two patients underwent traction preoperatively. Five patients had posterior fixation and fusion only and 2 patients had a combined anterior and posterior fixation and fusion. Overall, there was improvement in average pre/postoperative sagittal vertical axis (6.96 cm to 3.04 cm), T1 slope (33.61° to 24.34°), and C2-C7 lordosis (-21.65° to -0.03°).
Surgical correction of postradiation dropped head spinal deformity involving anterior and posterior fixation with osteotomies provides improvement in functional and radiographic outcomes as shown in our series. These cases are technically challenging and have a high rate of perioperative complications. Approaches must be tailored to the patient with attention to their specific surgical and radiation history.
垂头综合征是一种影响日常功能的病态,会导致疼痛、吞咽困难和呼吸功能受损。报道的垂头综合征的病因包括神经肌肉疾病、颈椎手术后的医源性疾病以及特发性疾病和头颈部癌症放疗后疾病。由于并发症发生率较高,这种脊柱疾病的治疗仍然具有挑战性。我们报告了 7 例因头颈部癌症放疗后颈椎畸形而接受手术矫正垂头综合征的患者系列。
这是对 2016 年至 2019 年间因放疗后颈椎畸形导致垂头综合征而接受手术的 7 例患者进行的回顾性研究。从病历中获得了临床变量。检查了手术前后的影像学参数,包括 T1 斜率、矢状垂直轴和 C2-C7 颈椎前凸角。
研究纳入 7 例患者,平均年龄 69 岁。2 例患者术前接受牵引。5 例患者仅行后路固定融合,2 例患者行前路和后路联合固定融合。总体而言,平均术前/术后矢状垂直轴(6.96cm 至 3.04cm)、T1 斜率(33.61°至 24.34°)和 C2-C7 前凸角(-21.65°至-0.03°)均有改善。
我们的研究结果表明,对于涉及前路和后路固定融合截骨术的放疗后垂头脊柱畸形,手术矫正可改善功能和影像学结果。这些病例技术上具有挑战性,围手术期并发症发生率高。手术方法必须根据患者的具体手术和放疗史量身定制。