Centre for Minimally Invasive Neurosurgery, Prince of Wales Private Hospital, Sydney, Australia.
Rutgers Robert Wood Johnson School of Medicine, New Brunswick, New Jersey, USA.
Oper Neurosurg (Hagerstown). 2021 Aug 16;21(3):E199-E214. doi: 10.1093/ons/opab174.
The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration with additional roles in attention, written language, and working memory. A detailed understanding of the exact location and nature of associated white matter tracts could improve surgical decisions and subsequent postoperative morbidity related to surgery in and around this gyrus.
To characterize the fiber tracts of the SPL based on relationships to other well-known neuroanatomic structures through diffusion spectrum imaging (DSI)-based fiber tracking validated by gross anatomical dissection as ground truth.
Neuroimaging data of 10 healthy, adult control subjects was obtained from a publicly accessible database published in Human Connectome Project for subsequent tractographic analyses. White matter tracts were mapped between both cerebral hemispheres, and a lateralization index was calculated based on resultant tract volumes. Post-mortem dissections of 10 cadavers identified the location of major tracts and validated our tractography results based on qualitative visual agreement.
We identified 9 major connections of the SPL: U-fiber, superior longitudinal fasciculus, inferior longitudinal fasciculus, inferior fronto-occipital fasciculus, middle longitudinal fasciculus, extreme capsule, vertical occipital fasciculus, cingulum, and corpus callosum. There was no significant fiber lateralization detected.
The SPL is an important region implicated in a variety of tasks involving visuomotor and visuospatial integration. Improved understanding of the fiber bundle anatomy elucidated in this study can provide invaluable information for surgical treatment decisions related to this region.
顶叶上回（SPL）参与躯体感觉和视空间整合，并且在注意力、书面语言和工作记忆方面具有额外的作用。详细了解与该回相关的白质束的确切位置和性质，可以改善手术决策，并降低与该脑回周围手术相关的术后发病率。
通过基于弥散张量成像（DTI）的纤维追踪来验证大体解剖学作为真实情况，基于与其他知名神经解剖结构的关系，对 SPL 的纤维束进行特征描述。
从人类连接组计划（HCP）的公开数据库中获取了 10 名健康成年对照者的神经影像学数据，用于随后的追踪分析。在两个大脑半球之间绘制白质束，并根据所得束体积计算侧化指数。对 10 具尸体进行死后解剖，确定主要束的位置，并根据定性视觉一致性验证我们的追踪结果。
我们确定了 SPL 的 9 个主要连接：U 纤维、上纵束、下纵束、下额枕束、中纵束、外囊、垂直枕束、扣带束和胼胝体。未检测到明显的纤维侧化。
SPL 是一个重要的区域，涉及到各种涉及视动和视空间整合的任务。本研究阐明的纤维束解剖结构的更好理解，可以为与该区域相关的手术治疗决策提供宝贵的信息。
