[献血者和癌症患者全血的天然抗肿瘤细胞毒性]
[Natural antitumor cytotoxicity of the whole blood of donors and cancer patients].
作者信息
Balashov K E, Letiagin V P, Ozherel'ev A S, Oleĭnikova O M, Kadagidze Z G
出版信息
Vopr Onkol. 1987;33(12):71-4.
PMID:3424710
Abstract
Natural antitumor resistance of cancer patients and healthy subjects was studied on the basis of whole blood natural cytotoxicity (WBNC) assay. A correlation between WBNC and mononuclear leukocyte cytotoxic activity in healthy donors was established (r = 0.912; p less than 0.001). WBNC levels in colonic, breast and gastric cancer patients were decreased as compared with healthy controls.
摘要
基于全血自然细胞毒性（WBNC）检测法，对癌症患者和健康受试者的天然抗肿瘤抗性进行了研究。在健康供体中，建立了WBNC与单核白细胞细胞毒性活性之间的相关性（r = 0.912；p < 0.001）。与健康对照组相比，结肠癌、乳腺癌和胃癌患者的WBNC水平降低。
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