Department of Neurology, Gülhane Training and Research Hospital, Ankara, Turkey
Department of Neurology, School of Medicine, Erciyes University, Kayseri, Turkey
Turk J Med Sci. 2021 Aug 30;51(4):1994-1999. doi: 10.3906/sag-2102-234.
BACKGROUND/AIM: The use of complementary and alternative medicine (CAM) is common in patients with primary headache. However, no study has been reported in which standardized modalities were questioned in a Turkish population. The aim of the present study was to investigate the frequency of CAM use and factors related to it in these patients. MATERIALS AND METHODS: Patients with a diagnosis of primary headache were included in this cross-sectional observational study. Demographic and disease specific characteristics were recorded. The use and effect of 15 CAM modalities were evaluated in accordance with the Traditional and Complementary Medicine Regulations. The patients were categorized into two groups according to their use of CAM procedures. Logistic regression analysis was further performed to assess the association between CAM use and related factors. RESULTS: One hundred twenty patients [101 (84.2%) female, mean age 38.20 ± 12.24 years] were included. Use of CAM was reported in 33.3% of the patients. The most frequently used CAM modalities were phytotherapy (37.5%), cupping (27.5%), and chiropractic adjustment (17.5%). Compared with nonusers, CAM users showed a longer duration of disease (respectively mean 5.68 ± 4.96 years and 10.97 ± 8.57 years, p = 0.000). There were no differences with respect to age, sex, education, presence of systemic disease, headache subtypes, number of headache days in a month, or headache severity. Patients who underwent cupping reported that they benefited more than those who tried phytotherapy and multiple CAM methods (respectively 45.5%, 33.3%, 16.6%, p = 0.039). Subsequently, the logistic regression analysis showed a significant association between only disease duration and CAM use [respectively p value, OR (95% CI), and confidence intervals = 0.002 (1.143 (1.050–1.243)]. CONCLUSION: Our results suggest that Turkish patients with primary headache, especially those with long disease duration, use CAM modalities. Larger population-based studies are required to clarify the safety and efficacy of these methods.
背景/目的：在原发性头痛患者中，补充和替代医学（CAM）的使用很常见。然而，目前还没有报告在土耳其人群中使用标准化方法对其进行研究。本研究的目的是调查这些患者中 CAM 使用的频率和相关因素。
材料和方法：本横断面观察性研究纳入了原发性头痛诊断患者。记录了人口统计学和疾病特异性特征。根据传统和补充医学法规评估了 15 种 CAM 方式的使用和效果。根据 CAM 程序的使用情况，将患者分为两组。进一步进行逻辑回归分析，以评估 CAM 使用与相关因素之间的关联。
结果：共纳入 120 例患者[101 例（84.2%）为女性，平均年龄 38.20±12.24 岁]。33.3%的患者使用了 CAM。最常使用的 CAM 方式为植物疗法（37.5%）、拔罐（27.5%）和脊椎指压疗法（17.5%）。与非使用者相比，CAM 使用者的疾病持续时间更长（分别为平均 5.68±4.96 年和 10.97±8.57 年，p=0.000）。年龄、性别、教育程度、是否存在系统性疾病、头痛亚型、每月头痛天数或头痛严重程度无差异。接受拔罐治疗的患者报告受益多于接受植物疗法和多种 CAM 方法的患者（分别为 45.5%、33.3%、16.6%，p=0.039）。随后，逻辑回归分析显示，仅疾病持续时间与 CAM 使用之间存在显著关联[分别为 p 值、比值比（95%CI）和置信区间=0.002（1.143（1.050-1.243）]。
结论：我们的结果表明，土耳其原发性头痛患者，特别是那些疾病持续时间较长的患者，使用 CAM 方式。需要进行更大规模的基于人群的研究，以明确这些方法的安全性和有效性。
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