Department of Equine Clinical Studies, School of Veterinary Medicine, University College Dublin, Dublin, Ireland (Vermedal); Department of Clinical Studies (Valverde) and Department of Population Medicine (Sears), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Can J Vet Res. 2021 Jul;85(3):193-200.
The objective of this study was to investigate the effect of anesthesia duration on the quality of recovery in horses. The medical records of horses that were anesthetized and underwent surgery for elective and emergency soft tissue and orthopedic conditions from 2013 to 2019 were reviewed. Horses included in the study (N = 305) fulfilled the following requirements: all had the same premedication/induction protocol and the same balanced anesthesia for maintenance and were anesthetized by the same, experienced Board-certified anesthesiologist. A standardized anesthetic recovery score was completed for all horses to evaluate their recovery and the following interactions were assessed: age, body weight, breed, sex, American Society of Anesthesiologists status, type of surgical procedure, occurrence of hypotension, use of dobutamine, number of additional doses of xylazine/ketamine after isoflurane discontinuation, anesthesia duration, post-anesthetic sedation, and end-tidal isoflurane concentration during maintenance and at the time of transfer to the recovery room. These interactions were assessed based on the quality of recovery score using logistic regression. Duration of anesthesia ( = 0.021) and age ( = 0.003) negatively affected the quality of recovery. The odds of a worse recovery score were increased by 1.20-fold (1.03, 1.41; lower and upper limits) for every additional 30 min of anesthesia duration, while the odds of a worse recovery score were increased by 1.09-fold (1.03, 1.16) for every additional 1 y of age. In conclusion, the results of this retrospective study indicate that increasing the anesthesia duration negatively affects the quality of recovery in horses undergoing routine and emergency surgical procedures.
本研究旨在探讨麻醉持续时间对马术后恢复质量的影响。对 2013 年至 2019 年间因择期和紧急软组织及骨科疾病接受麻醉和手术的马的病历进行了回顾。纳入研究的马匹（N=305）符合以下要求：均采用相同的术前/诱导方案和相同的平衡麻醉维持，且均由同一位经验丰富的、经董事会认证的麻醉师进行麻醉。所有马匹均完成标准化麻醉恢复评分以评估其恢复情况，并评估以下交互作用：年龄、体重、品种、性别、美国麻醉师协会状态、手术类型、低血压发生情况、是否使用多巴酚丁胺、异氟烷停药后是否需要额外给予二甲苯胺/氯胺酮、麻醉持续时间、麻醉后镇静以及维持时和转移至恢复室时的呼气末异氟烷浓度。这些交互作用是基于恢复质量评分使用逻辑回归进行评估的。麻醉持续时间（=0.021）和年龄（=0.003）对恢复质量有负面影响。麻醉持续时间每增加 30 分钟，恢复评分较差的可能性增加 1.20 倍（1.03，1.41；下限和上限），而年龄每增加 1 岁，恢复评分较差的可能性增加 1.09 倍（1.03，1.16）。总之，这项回顾性研究的结果表明，麻醉持续时间的增加会对接受常规和紧急手术的马的恢复质量产生负面影响。
