Berenson C S, Dobuler K J, Bia F J
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510.
Yale J Biol Med. 1987 Sep-Oct;60(5):437-45.
The diagnostic considerations raised by immunocompromised patients with opportunistic infection continue to expand. When such patients harbor latent or persistent infection acquired in a tropical environment, the diagnostic challenge is even greater. The Infectious Disease Service at Yale-New Haven Hospital was asked to see a middle-aged man from Peru with known T-cell lymphoma who had recently completed a course of chemotherapy. He presented to the hospital with fever, petechial skin rash, pulmonary infiltrates, and neutropenia. Ultimately this case illustrated the necessity for careful evaluation of such patients, looking, in particular, for evidence of opportunistic parasitic infection.
免疫功能低下患者发生机会性感染所引发的诊断考量持续增加。当这类患者携带在热带环境中获得的潜伏或持续感染时,诊断挑战就更大了。耶鲁 - 纽黑文医院的传染病科被要求诊治一名来自秘鲁的中年男子,他患有已知的T细胞淋巴瘤,近期刚完成一个化疗疗程。他因发热、皮肤瘀点皮疹、肺部浸润和中性粒细胞减少症入院。最终,该病例表明对此类患者进行仔细评估的必要性,尤其要寻找机会性寄生虫感染的证据。