Gehring W, Gloor M
Hautklinik am Klinikum der Stadt Karlsruhe.
Z Hautkr. 1987 Nov 1;62(21):1510, 1517-21.
9 patients suffering from mycosis fungoides in various stages were topically treated with dichlorodiethyl sulfide solution associated with photochemotherapy. Topical application of dichlorodiethyl sulfide is indicated in the stages 1 to 3. In more advanced stages, the cutaneous lesions showed good response to therapy, but systemic lesions could not be influenced. Only one patient developed sensitization to topical dichlorodiethyl sulfide. The low incidence of allergic complications may be due to the combined therapy of dichlorodiethyl sulfide and photochemotherapy.
9例处于不同阶段的蕈样肉芽肿患者接受了二氯二乙硫醚溶液联合光化学疗法的局部治疗。二氯二乙硫醚局部应用适用于1至3期。在更晚期阶段,皮肤病变对治疗有良好反应,但全身病变无法受到影响。仅1例患者对二氯二乙硫醚局部用药产生致敏。过敏并发症发生率低可能归因于二氯二乙硫醚与光化学疗法的联合治疗。