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俄罗斯大白猪遗传多样性与人工选择的全基因组分析。

Genome-wide analysis of genetic diversity and artificial selection in Large White pigs in Russia.

作者信息

Bakoev Siroj, Getmantseva Lyubov, Kostyunina Olga, Bakoev Nekruz, Prytkov Yuri, Usatov Alexander, Tatarinova Tatiana V

机构信息

Federal Research Center for Animal Husbandry named after Academy Member LK. Ernst, Dubrovitsy, Russia.

Centre for Strategic Planning and Management of Biomedical Health Risks, Moscow, Russia.

出版信息

PeerJ. 2021 Jul 2;9:e11595. doi: 10.7717/peerj.11595. eCollection 2021.

DOI:10.7717/peerj.11595
PMID:34249494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8256806/
Abstract

Breeding practices adopted at different farms are aimed at maximizing the profitability of pig farming. In this work, we have analyzed the genetic diversity of Large White pigs in Russia. We compared genomes of historic and modern Large White Russian breeds using 271 pig samples. We have identified 120 candidate regions associated with the differentiation of modern and historic pigs and analyzed genomic differences between the modern farms. The identified genes were associated with height, fitness, conformation, reproductive performance, and meat quality.

摘要

不同农场采用的养殖方法旨在实现养猪业利润最大化。在这项研究中,我们分析了俄罗斯大白猪的遗传多样性。我们使用271份猪样本比较了俄罗斯历史上和现代大白猪品种的基因组。我们确定了120个与现代猪和历史猪的分化相关的候选区域,并分析了现代农场之间的基因组差异。所确定的基因与身高、健康状况、体型、繁殖性能和肉质有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/d915ba5c1767/peerj-09-11595-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/de6b65463928/peerj-09-11595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/42d81b5662b3/peerj-09-11595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/a90555aad5ed/peerj-09-11595-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/d915ba5c1767/peerj-09-11595-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/de6b65463928/peerj-09-11595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/42d81b5662b3/peerj-09-11595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/a90555aad5ed/peerj-09-11595-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b34/8256806/d915ba5c1767/peerj-09-11595-g004.jpg

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G3 (Bethesda). 2020 Oct 5;10(10):3765-3773. doi: 10.1534/g3.120.401628.
2
Mitochondrial DNA Diversity in Large White Pigs in Russia.俄罗斯大白猪的线粒体DNA多样性
Animals (Basel). 2020 Aug 6;10(8):1365. doi: 10.3390/ani10081365.
3
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鉴定猪总产仔数的显著单核苷酸多态性及其与猪腿部肿块的关系。
Biology (Basel). 2024 Dec 11;13(12):1034. doi: 10.3390/biology13121034.
4
Evaluation of genetic differentiation and search for candidate genes for reproductive traits in pigs.猪生殖性状的遗传分化评估及候选基因筛选
Anim Biosci. 2024 May;37(5):832-838. doi: 10.5713/ab.23.0297. Epub 2024 Jan 20.
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Identification of ROH Islands Conserved through Generations in Pigs Belonging to the Nero Lucano Breed.鉴定属于 Nero Lucano 品种的猪中世代保守的 ROH 岛屿。
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