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1
Bowel visualization on the lymphoscintigraphy images of a bladder cancer patient due to inadvertent injection of the tracer in the rectal wall.一名膀胱癌患者在淋巴闪烁显像图像上出现肠道显影,原因是示踪剂意外注入直肠壁。
Asia Ocean J Nucl Med Biol. 2021 Spring;9(2):177-179. doi: 10.22038/AOJNMB.2021.54064.1370.
2
SPECT-CT for topographic mapping of sentinel lymph nodes prior to gamma probe-guided biopsy in head and neck squamous cell carcinoma.在头颈部鳞状细胞癌中,利用单光子发射计算机断层扫描-计算机断层扫描(SPECT-CT)在γ探针引导活检前对前哨淋巴结进行定位成像。
J Craniomaxillofac Surg. 2004 Dec;32(6):343-9. doi: 10.1016/j.jcms.2004.05.008.
3
Comparison of lymphoscintigraphy and single photon emission computed tomography with computed tomography (SPECT/CT) for sentinel lymph node detection in endometrial cancer.比较淋巴闪烁显像与单光子发射计算机断层扫描结合计算机断层扫描(SPECT/CT)在子宫内膜癌前哨淋巴结检测中的应用。
Int J Gynecol Cancer. 2020 May;30(5):626-630. doi: 10.1136/ijgc-2019-001154. Epub 2020 Mar 21.
4
[Contribution of nuclear medicine to lymphatic mapping and sentinel node identification in oncology].[核医学在肿瘤学中对淋巴绘图和前哨淋巴结识别的贡献]
Rev Esp Med Nucl. 1999;18(2):111-21.
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The Role of SPECT/CT Lymphoscintigraphy and Radioguided Sentinel Lymph Node Biopsy in Managing Papillary Thyroid Cancer.SPECT/CT 淋巴闪烁显像和放射性核素导向前哨淋巴结活检在甲状腺乳头状癌诊治中的作用。
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Head-to-head comparison of the hybrid tracer indocyanine green-99mTc-nanocolloid with 99mTc-Senti-Scint using sentinel node lymphoscintigraphy and single-photon emission computed tomography combined with computer tomography in melanoma.头对头比较混合示踪剂吲哚菁绿-99mTc-纳米胶体与 99mTc-Senti-Scint 在黑色素瘤前哨淋巴结淋巴闪烁显像和单光子发射计算机断层扫描与计算机断层扫描中的应用。
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7
Multi-slice SPECT/CT vs. lymphoscintigraphy and intraoperative gamma ray probe for sentinel node mapping in HNSCC.多层SPECT/CT与淋巴闪烁显像及术中γ射线探头在头颈部鳞状细胞癌前哨淋巴结定位中的比较
Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1633-1642. doi: 10.1007/s00405-016-4379-5. Epub 2016 Nov 11.
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Clinical Value of Single-photon Emission Computed Tomography Combined With Computed Tomography for Sentinel Lymph Node Identification in Melanoma.单光子发射计算机断层扫描联合计算机断层扫描在黑色素瘤前哨淋巴结识别中的临床价值
Ann Plast Surg. 2019 Apr;82(4S Suppl 3):S192-S194. doi: 10.1097/SAP.0000000000001895.
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Intraoperative sentinel node imaging versus SPECT/CT in oral cancer - A blinded comparison.口腔癌术中前哨淋巴结成像与 SPECT/CT 的对比:一项盲法比较。
Eur J Surg Oncol. 2018 Dec;44(12):1901-1907. doi: 10.1016/j.ejso.2018.08.026. Epub 2018 Sep 6.
10
Integration of hybrid single-photon emission computed tomography/computed tomography in the preoperative assessment of sentinel node in patients with cervical and endometrial cancer: our experience and literature review.混合单光子发射计算机断层扫描/计算机断层扫描在宫颈癌和子宫内膜癌前哨淋巴结评估中的应用:我们的经验和文献复习。
Int J Gynecol Cancer. 2012 Jun;22(5):830-5. doi: 10.1097/IGC.0b013e318253496f.

本文引用的文献

1
Sentinel lymph node biopsy in muscle-invasive bladder cancer: single-center experience.肌层浸润性膀胱癌前哨淋巴结活检:单中心经验。
Ann Nucl Med. 2020 Oct;34(10):718-724. doi: 10.1007/s12149-020-01502-6. Epub 2020 Jul 12.
2
Sentinel Node Biopsy in Urothelial Carcinoma of the Bladder: Systematic Review and Meta-Analysis.膀胱尿路上皮癌前哨淋巴结活检:系统评价与Meta分析
Urol Int. 2019;103(4):373-382. doi: 10.1159/000497310. Epub 2019 Mar 5.
3
Radio-guided sentinel lymph node detection and lymph node mapping in invasive urinary bladder cancer: a prospective clinical study.放射性引导下浸润性膀胱癌前哨淋巴结检测及淋巴结图谱绘制:一项前瞻性临床研究
BJU Int. 2017 Sep;120(3):329-336. doi: 10.1111/bju.13700. Epub 2016 Dec 4.
4
Sentinel node detection in muscle-invasive urothelial bladder cancer is feasible after neoadjuvant chemotherapy in all pT stages, a prospective multicenter report.一项前瞻性多中心报告表明,在新辅助化疗后,对所有pT分期的肌肉浸润性尿路上皮膀胱癌进行前哨淋巴结检测是可行的。
World J Urol. 2017 Jun;35(6):921-927. doi: 10.1007/s00345-016-1952-x. Epub 2016 Oct 13.
5
Radio-Guided Lymph Node Mapping in Bladder Cancer Using SPECT/CT and Intraoperative γ-Probe Methods.膀胱癌 SPECT/CT 与术中 γ 探测仪引导下的淋巴结示踪
Clin Nucl Med. 2016 Aug;41(8):e362-7. doi: 10.1097/RLU.0000000000001224.
6
Sentinel node biopsy in endometrial cancer: systematic review and meta-analysis of the literature.子宫内膜癌前哨淋巴结活检:文献的系统评价与荟萃分析
Eur J Gynaecol Oncol. 2013;34(5):387-401.
7
The accuracy of sentinel node biopsy in breast cancer patients with the history of previous surgical biopsy of the primary lesion: systematic review and meta-analysis of the literature.前次原发性病变手术活检史的乳腺癌患者前哨淋巴结活检的准确性:文献的系统评价和荟萃分析。
Eur J Surg Oncol. 2012 Feb;38(2):95-109. doi: 10.1016/j.ejso.2011.11.005. Epub 2011 Dec 3.
8
Accuracy of sentinel lymph node biopsy for inguinal lymph node staging of penile squamous cell carcinoma: systematic review and meta-analysis of the literature.经阴道超声联合磁共振成像在宫颈癌术前分期中的应用价值。
J Urol. 2012 Jan;187(1):25-31. doi: 10.1016/j.juro.2011.09.058. Epub 2011 Nov 16.
9
Sentinel node mapping in the prostate cancer. Meta-analysis.前列腺癌中的前哨淋巴结定位。荟萃分析。
Nuklearmedizin. 2011;50(3):107-15. doi: 10.3413/nukmed-0339-10-07. Epub 2011 Jan 25.
10
Hybrid SPECT-CT: an additional technique for sentinel node detection of patients with invasive bladder cancer.杂交单光子发射计算机断层显像-计算机断层扫描:浸润性膀胱癌患者前哨淋巴结检测的一种辅助技术。
Eur Urol. 2006 Jul;50(1):83-91. doi: 10.1016/j.eururo.2006.03.002. Epub 2006 Mar 20.

一名膀胱癌患者在淋巴闪烁显像图像上出现肠道显影,原因是示踪剂意外注入直肠壁。

Bowel visualization on the lymphoscintigraphy images of a bladder cancer patient due to inadvertent injection of the tracer in the rectal wall.

作者信息

Ghorbani Hamidreza, Zarifmahmoudi Leili, Sadeghi Ramin, Soltani Salman, Aghaee Atena

机构信息

Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Asia Ocean J Nucl Med Biol. 2021 Spring;9(2):177-179. doi: 10.22038/AOJNMB.2021.54064.1370.

DOI:10.22038/AOJNMB.2021.54064.1370
PMID:34250147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8255522/
Abstract

The effectiveness of the sentinel lymph node mapping in patients with Urothelial carcinoma of the bladder is under investigation. Single photon emission computed tomography (SPECT/CT) and intraoperative sentinel node biopsy using gamma probe are performed to detect the exact location of the sentinel lymph node to be dissected during the surgery. In this case report, a 73-year old man with high grade urothelial carcinoma was referred to our nuclear medicine department for SPECT/CT, four hours after injection of the radiotracer through cystoscopy. SPECT/CT could not reveal any sentinel node; however, one sentinel lymph node was detected and harvested in the right external iliac region during surgery. SPECT/CT revealed unusual accumulation of tracer in large bowel which was due to severe adhesion of rectum and bladder, and inadvertent injection of the radiotracer into the rectal wall. During the sentinel lymph node procedure, the tracer should be injected with extreme caution and lymphoscintigraphy post injection may help detection of any injection failures.

摘要

前哨淋巴结定位在膀胱尿路上皮癌患者中的有效性正在研究中。采用单光子发射计算机断层扫描(SPECT/CT)和术中使用γ探头进行前哨淋巴结活检,以确定手术中要切除的前哨淋巴结的确切位置。在本病例报告中,一名患有高级别尿路上皮癌的73岁男性,在通过膀胱镜注射放射性示踪剂4小时后,被转诊至我们核医学科进行SPECT/CT检查。SPECT/CT未发现任何前哨淋巴结;然而,手术期间在右髂外区域发现并切除了一个前哨淋巴结。SPECT/CT显示示踪剂在大肠中异常聚集,这是由于直肠与膀胱严重粘连,以及放射性示踪剂意外注入直肠壁所致。在前哨淋巴结手术过程中,注射示踪剂时应格外小心,注射后进行淋巴闪烁显像可能有助于发现任何注射失败情况。