Mølstad P, Nustad M
Department of Internal Medicine, Hamar Hospital, Norway.
Acta Med Scand. 1987;222(5):433-7. doi: 10.1111/j.0954-6820.1987.tb10961.x.
All patients hospitalized during a 3-year period with an acute myocardial infarction were followed for the occurrence of reinfarction or death. The patients with diabetes mellitus (n = 95) were compared with the non-diabetic population (n = 545). The diabetics had a higher mortality rate (relative death rate of 1.44 vs. 0.93, p less than 0.01) and a higher frequency of reinfarctions (18.9 vs. 10.8%, p = 0.04) than the non-diabetic population. A larger proportion of the diabetics had suffered a previous infarction, but the excess mortality was also present in those without a previous infarction. Established risk factors for death after myocardial infarction, such as age, infarct size, infarct localization and heart size, could not account for the difference in mortality. It is suggested that the increased mortality among the diabetics may be due to an increase in the rate of progression of the atherosclerotic heart disease.
对在3年期间因急性心肌梗死住院的所有患者进行随访，观察再梗死或死亡的发生情况。将糖尿病患者（n = 95）与非糖尿病患者群体（n = 545）进行比较。糖尿病患者的死亡率更高（相对死亡率为1.44，而非糖尿病患者为0.93，p < 0.01），再梗死发生率也更高（18.9% 对10.8%，p = 0.04）。糖尿病患者中曾患过心肌梗死的比例更大，但在未曾患过心肌梗死的患者中也存在过高的死亡率。心肌梗死后死亡的既定危险因素，如年龄、梗死面积、梗死部位和心脏大小，无法解释死亡率的差异。提示糖尿病患者死亡率增加可能是由于动脉粥样硬化性心脏病进展速度加快所致。
